See main article: 2021 BGL Luxembourg Open.
Coco Gauff and Caty McNally were the reigning champions, having won the last edition in 2019,[1] but chose not to defend their title.
Greet Minnen and Alison Van Uytvanck won the title, defeating Erin Routliffe and Kimberley Zimmermann in the final, 6–3, 6–3.