See main article: article and 2021 Abierto Zapopan.
Maria Sanchez and Fanny Stollár were the defending champions from when the tournament was last held in 2019,[1] but they lost in the semifinals to Ellen Perez and Astra Sharma.
Perez and Sharma went on to win the title, defeating Desirae Krawczyk and Giuliana Olmos in the final, 6–4, 6–4.