| Competition: | Nemzeti Bajnokság II |
| Season: | 2021–22 |
| Winners: | Vasas |
| Promoted: | Vasas Kecskemét |
| Relegated: | Szolnok Budaörs III. Kerület |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| Updated: | 4 August 2021 |
The 2021–22 Nemzeti Bajnokság II (also known as 2021–22 Merkantil Bank Liga) was Hungary's 71st season of the Nemzeti Bajnokság II, the second tier of the Hungarian football league system. The season began in July 2021.
The following teams have changed division since the 2020–21 season.
Following is the list of clubs competing in the league this season, with their location, stadium and stadium capacity.
| Team | Location | Stadium | Capacity[1] | data-sort-type="number" | 2019–20 |
|---|---|---|---|---|---|
| III. Kerület | Budapest | ||||
| Ajka | Ajka | Városi Stadion | 5,000 | 9th | |
| Békéscsaba | Békéscsaba | Kórház utcai Stadion | 2,479 | 15th | |
| Csákvár | Csákvár | Tersztyánszky Ödön Stadion | 2,020 | 4th | |
| Budaörs | Budaörs | Árok utcai Stadion | 604 | 11th | |
| Dorog | Dorog | Buzánszky Jenő Stadion | 5,000 | 13th | |
| Győr | Győr | ETO Park | 15,600 | 6th | |
| Kecskemét | Kecskemét | Széktói Stadion | |||
| Nyíregyháza | Nyíregyháza | Városi Stadion | 10,300 | 8th | |
| Pécs | Pécs | Stadion PMFC | 7,000 | 1st (NB III, Central) | |
| Siófok | Siófok | Révész Géza utcai Stadion | 6,500 | 5th | |
| Soroksár | Budapest (Soroksár) | Szamosi Mihály Sportelep | 5,000 | 10th | |
| Szeged-Csanád | Szeged | Szent Gellért Fórum | 8,136 | 12th | |
| Szentlőrinc | Szentlőrinc | Szentlőrinci Sportpálya | 1,020 | 2nd (NB III, Central) | |
| Szolnok | Szolnok | Tiszaligeti Stadion | 3,437 | 16th | |
| Szombathelyi Haladás | Szombathely | Haladás Sportkomplexum | 8,940 | 17th | |
| Tiszakécske | Tiszakécske | 17th | |||
| Vasas | Budapest (Angyalföld) | Illovszky Rudolf Stadion | 5,154 | 3rd |
| Team | Head coach | Captain | Kit manufacturer | Shirt sponsor | |
|---|---|---|---|---|---|
| Ajka |  Károly Kis | Zoltán Kenderes | Zeus | – | |
| Békéscsaba | Sándor Preisinger | Sándor Nagy | Saller | Békés Drén | |
| Budaörs | Tibor Márkus | Ziccer | Volkswagen | ||
| Csákvár | Ede Visinka | 2Rule | Euroaszfalt | ||
| Dorog | Szabolcs Németh | Áron Mészáros | Adidas | Pannon Falap-Lemez | |
| Győri ETO | Barna Dobos | Adidas | WKW | ||
| Nyíregyháza | György Gálhidi | Ferenc Fodor | Jako | Révész | |
| Pécs | László Vas | Zsombor Futó | Macron | – | |
| Siófok | István Gál | Nike | HunGast | ||
| Soroksár | Péter Lipcsei | Nike | Soroksár District | ||
| Szeged-Csanád | Barna Dobos | Tamás Germán | hummel | – | |
| Szentlőrinc |  Marián Sluka | Macron | – | ||
| Szolnok | József Csábi | hummel | – | ||
| Szombathelyi Haladás | János Mátyus | 2Rule | – | ||
| Vasas | Szabolcs Schindler | Adidas | Alprosys |
| Central Hungary | Great Plain and North | |
|---|---|---|
| 8 Teams | 5 Teams | 5 Teams |