| Club: | Manchester City Women |
| Season: | 2021–22 |
| Manager: | Gareth Taylor |
| Chairman: | Khaldoon Mubarak |
| Stadium: | Academy Stadium |
| League: | FA WSL |
| League Result: | 3rd |
| Cup1: | FA Cup |
| Cup1 Result: | Runners-up |
| Cup2: | League Cup |
| Cup2 Result: | Winners |
| Cup4 Result: | Second qualifying round |
| League Topscorer: | Lauren Hemp (10 goals) |
| Season Topscorer: | Lauren Hemp (21 goals) |
| Highest Attendance: | 5,317 (vs. Manchester United, 13 February) |
| Lowest Attendance: | 1,098 (vs. Aston Villa, 20 November) |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was Manchester City Women's Football Club's 34th season of competitive football and their ninth season in the FA Women's Super League, the highest level of English women's football.
See main article: 2021–22 FA WSL.
See main article: 2021–22 Women's FA Cup. As a member of the first tier, Manchester City entered the FA Cup in the fourth round proper.
See main article: 2021–22 FA Women's League Cup. As a result of failing to progress from the Champions League qualifying rounds, Manchester City entered the FA Women's League Cup at the group stage. With the groups already drawn prior to their elimination, they were placed into the existing group of four in their geographical region.[1]
Group stage
Knockout stage
See main article: 2021–22 UEFA Women's Champions League. Manchester City entered the revised format of the Champions League in the second qualifying round.
Second qualifying round
Starting appearances are listed first, followed by substitute appearances after the + symbol where applicable.|-|colspan="14"|Players who appeared for the club but left during the season:|}
| Date | Position | No. | Player | From club |
|---|---|---|---|---|
| 11 June 2021 | MF | 30 | Ruby Mace | Arsenal[2] |
| 17 June 2021 | FW | 21 |  Khadija Shaw |  Bordeaux[3] |
| 5 July 2021 | MF | 17 |  Vicky Losada | Barcelona[4] |
| 18 August 2021 | FW | 13 |  Hayley Raso | Everton[5] |
| 27 August 2021 | DF | 33 | Alanna Kennedy | Tottenham Hotspur[6] |
| 2 September 2021 | MF | 12 |  Filippa Angeldal | BK Häcken[7] |
| 27 January 2022 | MF | 41 |  Julie Blakstad | Rosenborg[8] |
| Date | Position | No. | Player | To club | |
|---|---|---|---|---|---|
| 17 May 2021 | MF | 21 |  Rose Lavelle | OL Reign[9] | |
| MF | 22 | Sam Mewis | North Carolina Courage[10] | ||
| DF | 5 |  Megan Campbell | Liverpool[11] [12] | ||
| 1 July 2021 | DF | 2 | Aoife Mannion | Manchester United[13] [14] | |
| MF | 12 | Tyler Toland | Celtic[15] | ||
| FW | 17 |  Lee Geum-min | Brighton & Hove Albion[16] | ||
| 20 August 2021 | DF | 13 | Abby Dahlkemper | Houston Dash[17] [18] | |
| 1 April 2022 | FW | 11 |  Janine Beckie | Portland Thorns[19] |