| Competition: | Liga Portugal 2 |
| Season: | 2021–22 |
| Winners: | Rio Ave |
| Promoted: | Rio Ave Casa Pia Chaves |
| Relegated: | Académica Varzim |
| Dates: | August 2021 – May 2022 |
| Matches: | 306 |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| Updated: | 30 May 2021 |
The 2021–22 Liga Portugal 2, also known as Liga Portugal SABSEG for sponsorship reasons, was the 32nd season of Portuguese football's second-tier league, and the second season under the current Liga Portugal 2 title. A total of 18 teams were competing in this division, including reserve sides from top-flight Primeira Liga teams.
A total of 18 teams contest the league, including 13 sides from the 2020–21 season, 3 teams relegated from the 2020–21 Primeira Liga and 2 promoted from the 2020–21 Campeonato de Portugal.
Farense and Nacional were relegated to 2021–22 Liga Portugal 2 after finishing in 17th and 18th placed teams in 2020–21 Primeira Liga.
Rio Ave were relegated after finishing in 16th place in 2020–21 Primeira Liga and losing the Relegation play-offs against Arouca.
Trofense[1] (promoted after a six-year absence) and Estrela da Amadora (promoted for the first time)[2] were promoted from the 2020–21 Campeonato de Portugal, replacing Oliveirense and Cova da Piedade.
Cova da Piedade failed to produce valid licensing documentation to compete in the 2021–22 season of the Liga Portugal 2, so they have been relegated by the Portuguese Football Professional League to the Liga 3. As a result, Vilafranquense, that finished in 17th place in the 2020–21 Liga Portugal 2 were invited to play in the second tier for the 2021–22 season.[3]
Relegated from 2020–21 Primeira Liga
Promoted from 2020–21 Campeonato de Portugal
Promoted to 2021–22 Primeira Liga
Relegated to 2021–22 Liga 3
The relegation play-offs took place on 21 and 29 May 2022.
Sporting Covilhã won 2–0 on aggregate and will play in the 2022–23 Liga Portugal 2; Alverca will play in the 2022–23 Liga 3.
The table lists the positions of teams after each week of matches. In order to preserve chronological evolvements, any postponed matches are not included to the round at which they were originally scheduled, but added to the full round they were played immediately afterwards.
| Month | Player of the Month | Goalkeeper of the Month | Defender of the Month | Midfielder of the Month | Forward of the Month | Manager of the Month | Goal of the Month | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Player | Club | Player | Club | Player | Club | Player | Club | Player | Club | Manager | Club | Player | Club | ||
| August | Guga | Rio Ave |  Jhonatan | Rio Ave | Aderllan Santos | Rio Ave | Guga | Rio Ave |  Saviour Godwin | Casa Pia | Luís Freire | Rio Ave | |||
| September | Heliardo | Varzim | Caio Secco | Penafiel | Ícaro Silva | Feirense |  Samba Koné | Porto B | Heliardo | Varzim | Rui Ferreira | Feirense | |||
| October/November | Jota | Casa Pia | Ricardo Batista | Casa Pia | Vasco Fernandes | Casa Pia | Paulo Bernardo | Benfica B | Jota | Casa Pia | Nélson Veríssimo | Benfica B | Fábio Fortes | Académica | |
| December | Bryan Róchez | Nacional | Tomás Araújo | Benfica B | João Teixeira | Chaves | Bryan Róchez | Nacional | Vítor Campelos | Chaves | Umaro Embaló | Benfica B | |||
| January | João Teixeira | Chaves | Alexsandro | Chaves | Wellington Carvalho | Chaves | Diogo Pinto | Estrela da Amadora | |||||||
| February | João Carlos | Académica | Vasco Fernandes | Casa Pia | João Carlos | Académica | Filipe Martins | Casa Pia | Traquina | Académica | |||||
| March | Zé Tiago | Varzim | Jhonatan | Rio Ave | André Almeida | Sp. Covilhã | Zé Tiago | Varzim | José Mota | Leixões | Tiago Gouveia | Benfica B | |||
| April | Edson Farias | Penafiel | Caio Secco | Penafiel | Edson Farias | Penafiel | Guga | Rio Ave | Wellington Carvalho | Chaves | Vítor Campelos | Chaves | |||
