| Country: | Italy |
| Season: | 2021–22 |
| Division1: | Serie A |
| Champions1: | Milan |
| Division2: | Serie B |
| Champions2: | Lecce |
| Division3: | Serie C |
| Champions3: | Südtirol (Group A) Modena (Group B) Bari (Group C) |
| Division4: | Serie D |
| Champions4: | Recanatese |
| Domestic: | Coppa Italia |
| Dchampions: | Internazionale |
| Supercup: | Supercoppa Italiana |
| Schampions: | Internazionale |
| Domestic2: | Coppa Italia Serie C |
| Dchampions2: | Padova |
| Wdivision1: | Serie A |
| Wchampions1: | Juventus |
| Wdomestic: | Coppa Italia |
| Wdchampions: | Juventus |
| Wsupercup: | Supercoppa Italiana |
| Wschampions: | Juventus |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| Flagicon: | yes |
The 2021–22 season was the 120th season of competitive football in Italy.
See main article: Italy national football team.
See main article: 2021 UEFA Nations League Finals.
See main article: 2022 FIFA World Cup qualification (UEFA).
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See main article: 2022 FIFA World Cup qualification – UEFA Group C.
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See main article: 2022 FIFA World Cup qualification – UEFA second round.
See main article: UEFA Euro 2020.
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See main article: UEFA Euro 2020 knockout phase.
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See main article: UEFA Euro 2020 Final.
See main article: 2022 Finalissima.
See main article: 2022–23 UEFA Nations League.
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See main article: Italy women's national football team.
See main article: 2023 FIFA Women's World Cup qualification (UEFA).
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See main article: 2023 FIFA Women's World Cup qualification – UEFA Group G.
See main article: 2022 Algarve Cup.
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Teams promoted to Serie A
Teams relegated from Serie A
Teams promoted to Serie B
Teams relegated from Serie B
See main article: 2021–22 Serie A.
See main article: 2021–22 Serie B.
See main article: 2021–22 Serie C.
See main article: 2021–22 Serie D.
See main article: 2021–22 Serie A (women).
See main article: 2021–22 Coppa Italia.
See main article: 2022 Coppa Italia Final.
See main article: 2021 Supercoppa Italiana.
See main article: 2021–22 Coppa Italia Serie C.
See main article: 2021–22 Coppa Italia Serie D.
See main article: 2021–22 Supercoppa Italiana (women).
See main article: 2021–22 UEFA Champions League.
See main article: 2021–22 UEFA Champions League knockout phase.
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See main article: 2021–22 UEFA Europa League.
See main article: 2021–22 UEFA Europa League knockout phase.
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See main article: 2021–22 UEFA Europa Conference League.
See main article: 2021–22 UEFA Europa Conference League qualifying phase and play-off round (Main Path).
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See main article: 2021–22 UEFA Europa Conference League knockout phase.
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See main article: 2022 UEFA Europa Conference League Final.
See main article: 2021–22 UEFA Youth League.
See main article: 2021–22 UEFA Youth League group stage.
See main article: 2021–22 UEFA Youth League Domestic Champions Path.
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See main article: 2021–22 UEFA Women's Champions League.
See main article: 2021–22 UEFA Women's Champions League qualifying rounds.
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See main article: 2021–22 UEFA Women's Champions League knockout phase.
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