| Mode: | Basketball |
| Sex: | none |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | UTSA Roadrunners women's |
| Conference: | Conference USA |
| Short Conf: | CUSA |
| Division: | West Division |
| Record: | 7-23 |
| Conf Record: | 3–11 |
| Hc Year: | 1st |
| Asst Coach1: | Empress Davenport |
| Asst Coach2: | Cameron Miles |
The 2021–22 UTSA Roadrunners women's basketball team represents the University of Texas at San Antonio during the 2021–22 NCAA Division I women's basketball season. The team is led by first-year head coach Karen Aston, and plays their home games at the Convocation Center in San Antonio, Texas as a member of Conference USA.[1]
|-!colspan=12 style=|Non-conference regular season|-!colspan=12 style=|CUSA regular season|-!colspan=12 style=| CUSA Tournament