| Mode: | basketball |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | UMass Lowell River Hawks |
| Conference: | America East Conference |
| Short Conf: | America East |
| Record: | 15–16 |
| Conf Record: | 7–11 |
| Head Coach: | Pat Duquette |
| Hc Year: | 9th |
| Asst Coach1: | Louis Hinnant |
| Asst Coach2: | Biko Paris |
| Asst Coach3: | Jon Iati |
| Stadium: | Costello Athletic Center |
The 2021–22 UMass Lowell River Hawks men's basketball team represented the University of Massachusetts Lowell in the 2021–22 NCAA Division I men's basketball season. They played their home games at the Costello Athletic Center in Lowell, Massachusetts and were led by ninth-year head coach Pat Duquette. They finished the season 15-16, 7-11 in America East Play to finish in 7th place. They lost in the quarterfinals of the America East tournament to UMBC.
In a season limited due to the ongoing COVID-19 pandemic, the River Hawks finished the 2020–21 season 11–12, 7–8 in America East play to finish in sixth place. They fell to Hartford in the America East Conference Championship.[1]
|-!colspan=12 style=| Non-conference regular season|-!colspan=12 style=| America East regular season|-!colspan=12 style=| America East tournamentSource[2]