| UAE President's Cup | |
| Year: | 2021–22 |
| Country: | United Arab Emirates |
| Dates: | 10 September 2021 – 21 October 2022 |
| Num Teams: | 16 (Knockout round) 30 (Total) |
| Defending Champions: | Shabab Al Ahli |
| Champions: | Sharjah |
| Count: | 9 |
| Runner-Up: | Al Wahda |
| Matches: | 13 |
| Goals: | 24 |
| Top Goal Scorer: | Ahmed Abunamous Fábio Lima Gilberto (2 goals each) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 UAE President's Cup was the 45th edition of the UAE President's Cup, Shabab Al Ahli were the defending champions after winning the last season's President's Cup, but were knocked out in the quarter-finals by eventual champions Sharjah.
| Round | Clubs | Winners from previous round | New entries this round | Leagues entering | |
|---|---|---|---|---|---|
| Preliminary round | 16 | 0 | 16 | 16 UAE First Division League teams | |
| Preliminary round play-offs | 4 | 4 | 0 | ||
| Round of 16 | 16 | 2 | 14 | 14 UAE Pro League teams | |
| Quarter-finals | 8 | 8 | 0 | ||
| Semi-finals | 4 | 4 | 0 | ||
| Final | 2 | 2 | 0 |
| Round | Draw date | Draw venue | Reference | |
|---|---|---|---|---|
| Preliminary round | 31 August 2021 | Dubai | [1] [2] | |
| Round of 16 | 14 November 2021 | Dubai | [3] | |
| Quarter-finals | 28 December 2021 | Abu Dhabi | [4] | |
| Semi-finals | 18 January 2022 | Dubai | [5] |
The preliminary round is contested between the 16 teams in the UAE First Division League, divided into four groups of four, the winners of each group will advance into a play off round.
All times are local (UTC+04:00)
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Ahmed Abunamous | Baniyas | 2 |
 Nicolás Giménez | |||
 Gilberto | Al Wasl | ||
| Fábio Lima | |||
| João Pedro | Al Wahda | ||
 Omar Kharbin | |||
| 2 | 18 Players | 1 |