| 2021–22 Top10 | |
| Countries: |  Italy |
| Date: | 24 September 2021 – 28 May 2022 |
| Champions: | Petrarca (14th title) |
| Runnersup: | Rovigo |
| Relegated: | Lazio |
| Matches: | 95 |
| Top Point Scorer: | Abner van Reenen (206) |
| Top Try Scorer: | Lorenzo Bruno Luhandre Luus (13) |
| Website: | https://www.federugby.it |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 Top10 was the 92nd edition of the Italian rugby union championship. Petrarca Rugby won their 14th title, after beating defending champions Rugby Rovigo Delta 19–6.
| Club | City | Stadium | Previous season |
|---|---|---|---|
| Calvisano | Calvisano | Stadio San Michele | Semifinals (3rd in league) |
| Colorno | Colorno | Stadio Giulio Maini | 9th |
| Fiamme Oro | Rome | Centro Sportivo Polizia di Stato | 7th |
| Lazio | Rome | Centro Sportivo Giulio Onesti | 10th |
| Lyons | Piacenza | Stadio Walter Beltrametti | 8th |
| Mogliano | Mogliano Veneto | Stadio Maurizio Quaggia | 6th |
| Petrarca | Padua | Centro sportivo Memo Geremia | 2nd |
| Rovigo | Rovigo | Stadio Comunale Mario Battaglini | 1st |
| Valorugby Emilia | Reggio Emilia | Stadio Mirabello | Semifinals (4th in league) |
| Viadana | Viadana | Stadio Luigi Zaffanella | 5th |
The top four teams at the end of the regular season (after all the teams played one another twice, once at home, once away) enter a knockout stage to decide the Champions of Italy. This consists of two rounds: semi-finals and final.
A new bonus points system was introduced in this season:[1]
| Team | Games | Points | Bonus points | Table points | Qualification | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pld | W | D | L | PF | PA | PD | ||||||
| 1 | Petrarca | 18 | 16 | 0 | 2 | 623 | 304 | +319 | 14 | 78 | Play-off | |
| 2 | Rovigo | 18 | 14 | 0 | 4 | 604 | 344 | +260 | 11 | 67 | ||
| 3 | Valorugby Emilia | 18 | 13 | 0 | 5 | 634 | 428 | +206 | 14 | 66 | ||
| 4 | Calvisano | 18 | 11 | 1 | 6 | 529 | 407 | +122 | 9 | 55 | ||
| 5 | Colorno | 18 | 9 | 1 | 8 | 553 | 560 | -7 | 7 | 45 | ||
| 6 | Fiamme Oro | 18 | 9 | 0 | 9 | 497 | 533 | -36 | 7 | 41 | ||
| 7 | Viadana | 18 | 5 | 1 | 12 | 417 | 577 | −160 | 6 | 28 | ||
| 8 | Lyons | 18 | 6 | 1 | 11 | 410 | 619 | −209 | 2 | 28 | ||
| 9 | Mogliano | 18 | 4 | 0 | 14 | 415 | 600 | −185 | 7 | 23 | ||
| 10 | Lazio | 18 | 1 | 0 | 17 | 437 | 747 | −310 | 7 | 12 | Serie A 2022–23 | |