| Club: | Ternana |
| Season: | 2021–22 |
| Chairman: | Stefano Ranucci |
| Owner: | Stefano Bandecchi |
| Manager: | Cristiano Lucarelli |
| Stadium: | Stadio Libero Liberati |
| League: | Serie B |
| League Result: | 10th |
| Cup1: | Coppa Italia |
| Cup1 Result: | Second round |
| League Topscorer: | Alfredo Donnarumma (14) |
| Season Topscorer: | Alfredo Donnarumma (15) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was Ternana Calcio's first season back in second division of the Italian football league, the Serie B, and the 97th as a football club.
See main article: 2021–22 Serie B.
The league fixtures were announced on 24 July 2021.[1]
See main article: 2021–22 Coppa Italia.