| Mode: | Women's Basketball |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | South Alabama Jaguars |
| Conference: | Sun Belt Conference |
| Short Conf: | Sun Belt |
| Record: | 8–18 |
| Conf Record: | 2–10 |
| Head Coach: | Terry Fowler |
| Hc Year: | 8th |
| Asst Coach1: | Dan Presel |
| Asst Coach2: | Rachel Travis |
| Asst Coach3: | Mansa El |
| Stadium: | Mitchell Center |
The 2021–22 South Alabama Jaguars women's basketball team represented the University of South Alabama during the 2021–22 NCAA Division I women's basketball season. The basketball team, led by eighth-year head coach Terry Fowler, played all home games at the Mitchell Center along with the South Alabama Jaguars men's basketball team. They were members of the Sun Belt Conference.
|-!colspan=9 style=| Exhibition|-|-!colspan=9 style=| Non-conference Regular Season|-|-!colspan=9 style=| Conference Regular Season|-|-!colspan=9 style=| Sun Belt Tournament[1]