| Season: | 2021–22 |
| League Topscorer: | Milan Vidakov (18 goals) |
| Matches: | 296 |
| Total Goals: | 691 |
| Longest Wins: | IMT 7 games |
| Longest Unbeaten: | IMT 14 games |
| Longest Winless: | Kabel 19 games |
| Longest Losses: | Kabel 11 games |
| Nextseason: | 2022–23 |
The 2021–22 Serbian First League is the 17th season of the Serbian First League since its establishment.
The league consist of 16 teams: eight teams from the 2020–21 Serbian First League, six teams relegated from 2020–21 Serbian SuperLiga and two new teams promoted from Serbian League.[1]
| Team | City | Stadium | Capacity | |
|---|---|---|---|---|
| Budućnost | Belgrade | Stadion FK Budućnost | 1,000 | |
| Grafičar | Belgrade | Topčiderska zvezda | 1,000 | |
| IMT | Belgrade | Stadion FK IMT | 1,150 | |
| Inđija | Inđija | Inđija Stadium | 4,500 | |
| Javor Matis | Ivanjica | Javor Stadium | 3,000 | |
| Kabel | Novi Sad | FK Kabel Stadium | 2,000 | |
| Loznica | Loznica | Lagator Stadium | 5,000 | |
| Mačva | Šabac | Mačva Stadium | 5,494 | |
| Mladost GAT | Novi Sad | Stadion FK Mladost | 200 | |
| OFK Bačka | Bačka Palanka | Stadion Slavko Maletin Vava | 4,000 | |
| Žarkovo | Belgrade | Žarkovo Stadium | 610 | |
| Rad | Belgrade | King Peter I Stadium | 3,919 | |
| Radnički | Sremska Mitrovica | Stadion FK Radnički | 2,000 | |
| Timok 1919 | Zaječar | Zaječar City Stadium | 10,000 | |
| Železničar | Pančevo | SC Mladost | 1,200 | |
| Zlatibor | Čajetina | Užice City Stadium | 15,000 |
The top eight teams advanced from the regular season. Teams played each other once.
The bottom eight teams from the regular season play in the relegation round. Teams play each other once.
As of matches played on 22 May 2022.[2]
| Pos | Scorer | Teams | Goals |
|---|---|---|---|
| 1 |  Milan Vidakov | Mladost GAT | 18 |
| 2 | Javor | 14 | |
| 3 | Borisav Burmaz | Grafičar | 12 |
| Vladimir Lučić | IMT | ||
| 5 | Luka Gojković | Rad | 11 |
| Vladan Milosavljev | Inđija | ||
| Železničar | |||
| Vladimir Radočaj | IMT |
| Player | For ! | Against | Result | Date | |
|---|---|---|---|---|---|
| Železničar | 3–0 | ||||
| Inđija | 4–0 | ||||
| Luka Čumić 4 | Zlatibor | 7–0 | |||
| Grafičar | Zlatibor | 5–1 | |||
| Javor | Kabel | 4–0 | |||
| Borisav Burmaz | Grafičar | Kabel | 5–0 | ||
| Borisav Burmaz 4 | Grafičar | Rad | 4–0 |