| Club: | SV Waldhof Mannheim |
| Season: | 2021–22 |
| Chairman: | Bernd Beetz |
| Manager: | Patrick Glöckner |
| Stadium: | Carl-Benz-Stadion |
| League: | 3. Liga |
| League Result: | 5th |
| Cup1: | DFB-Pokal |
| Cup1 Result: | Second round |
| Prevseason: | 2020–21 |
The 2021–22 season was the 115th in the history of SV Waldhof Mannheim and their third consecutive season in the third division. The club participated in 3. Liga and DFB-Pokal.
See main article: 2021–22 3. Liga.
The league fixtures were announced on 1 July 2021.[1]
See main article: 2021–22 DFB-Pokal.