| Club: | SPAL |
| Chairman: | Joe Tacopina |
| Mgrtitle: | Head coach |
| Manager: | Roberto Venturato |
| Stadium: | Stadio Paolo Mazza |
| League: | Serie B |
| League Result: | 15th |
| Cup1: | Coppa Italia |
| Cup1 Result: | First round |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was S.P.A.L.'s second consecutive season in second division of the Italian football league, the Serie B, and the 115th as a football club.
See main article: 2021–22 Serie B.
The league fixtures were announced on 24 July 2021.[1]
See main article: 2021–22 Coppa Italia.