| Competition: | Rwanda Premier League |
| Season: | 2021–22 |
| Winners: | APR |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | APR |
| Continentalcup2: | Confederation Cup |
| Continentalcup2 Qualifiers: | AS Kigali |
| League Topscorer: | Shabani Hussein (AS Kigali, 15 goals)[1] |
| Matches: | 240 |
| Total Goals: | 510 |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 Rwanda Premier League was a season of the Rwanda Premier League, the top-tier football league in Rwanda.
APR FC won their third consecutive league title on the last day of the season, defeating Police 2–0 with two second half goals to claim the top spot over Kiyovu Sports.[2]
Etoile de l'Est and Gicumbi FC were promoted after qualifying to the second division play-off final, replacing Sunrise and AS Muhanga. Etoile de L'Est returned to the top flight after a 24-year absence.[3]