| Mode: | Basketball |
| Sex: | none |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | Rice Owls women's |
| Conference: | Conference USA |
| Short Conf: | CUSA |
| Division: | West Division |
| Record: | 14–13 |
| Conf Record: | 8–9 |
| Hc Year: | 1st |
| Asst Coach1: | Lakevia Boykin |
| Asst Coach2: | Nick Grant |
| Asst Coach3: | Tiffany Morton |
The 2021–22 Rice Owls women's basketball team represented Rice University during the 2021–22 NCAA Division I women's basketball season. The team was led by first-year head coach Lindsay Edmonds, and played their home games at the Tudor Fieldhouse in Houston, Texas as a member of Conference USA.[1]
|-!colspan=12 style=|Non-conference regular season|-!colspan=12 style=|CUSA regular season|-!colspan=9 style=| Conference USA Tournament