| Club: | Real Madrid Femenino |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: | Florentino Pérez |
| Mgrtitle: | Coach |
| Manager: | David Aznar (until 29 November) (from 29 November) |
| Stadium: | Alfredo Di Stéfano Stadium |
| League: | Primera División |
| League Result: | 3rd |
| Cup1: | Copa de la Reina |
| Cup1 Result: | Semi-finals |
| Cup2: | Supercopa de España |
| Cup2 Result: | Semi-finals |
| Cup3: | UEFA Champions League |
| Cup3 Result: | Quarter-finals |
| League Topscorer: | Esther González (14) |
| Season Topscorer: | Esther González (17) |
| Highest Attendance: | 3,318 vs Barcelona, UEFA Women's Champions League, 22 March 2022 |
| Largest Win: | 5–0 vs Breiðablik, UEFA Women's Champions League, 13 October 2021 |
| Largest Loss: | 0–5 vs Barcelona, Primera División, 13 March 2022 |
| Pattern Name1: | Home |
| Pattern La1: | _realmadrid2122H |
| Pattern B1: | _realmadrid2122H |
| Pattern Ra1: | _realmadrid2122H |
| Pattern Sh1: | _realmadrid2122H |
| Pattern So1: | _realmadrid2122H |
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| Rightarm1: | FFFFFF |
| Shorts1: | FFFFFF |
| Socks1: | FFFFFF |
| Pattern Name2: | Away |
| Pattern La2: | _realmadrid2122A |
| Pattern B2: | _realmadrid2122A |
| Pattern Ra2: | _realmadrid2122A |
| Pattern Sh2: | _realmadrid2122A |
| Pattern So2: | _realmadrid2122Al |
| Leftarm2: | 28315C |
| Body2: | 28315C |
| Rightarm2: | 28315C |
| Shorts2: | 28315C |
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| Pattern Name3: | Third |
| Pattern B3: | _realmadrid2122t |
| Pattern Sh3: | _realmadrid2122t |
| Pattern So3: | _3_stripes_white |
| Leftarm3: | 2BB6BB |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 6th season in the existence of Real Madrid Femenino and the club's 2nd season after being officially rebranded as part of Real Madrid.[1] In addition to the domestic league, they participated in the Copa de la Reina. By virtue of their performances the previous season, the club also competed in the UEFA Women's Champions League and the Supercopa de España for the very first time.
David Aznar returned for his fourth campaign as a coach but was sacked and replaced by Alberto Toril after the club's draw with Alavés on match day eleven.[2]
See main article: 2021–22 Primera División (women).
See main article: 2021–22 UEFA Women's Champions League.
See main article: 2021–22 UEFA Women's Champions League qualifying rounds.
The second round draw was held on 22 August 2021.[3]
Real Madrid won 2–1 on aggregate.
The group stage draw was held on 13 September 2021.[4]