| Club: | Nîmes Olympique |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: | Rani Assaf |
| Mgrtitle: | Head coach |
| Manager: | Nicolas Usaï |
| League: | Ligue 2 |
| League Result: | 9th |
| Cup1: | Coupe de France |
| Cup1 Result: | Round of 64 |
| League Topscorer: | Moussa Koné (11) |
| Season Topscorer: | Yassine Benrahou Moussa Koné (12 each) |
| Pattern La1: | _NîmesO2122h |
| Pattern B1: | _NîmesO2122h |
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| Pattern B2: | _NîmesO2122a |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 35th season in the existence of Nîmes Olympique and the club's first season back in the second division of French football. In addition to the domestic league, Nîmes participated in this season's edition of the Coupe de France.
| scope=col | Player | Transferred to | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 25 | Rennes | €3M | [1] |
See main article: 2021–22 Ligue 2.
The league fixtures were announced on 25 June 2021.[2] [3]
See main article: 2021–22 Coupe de France.