| Mode: | Women's basketball |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | Missouri Tigers |
| Conference: | Southeastern Conference |
| Short Conf: | SEC |
| Record: | 18–13 |
| Conf Record: | 7–9 |
| Hc Year: | 12th |
| Asst Coach1: | Ashleen Bracey |
| Asst Coach2: | Chris Bracey |
| Asst Coach3: | Jenny Putnam |
| Bowl Result: | First Round |
The 2021–22 Missouri Tigers women's basketball team represented the University of Missouri during the 2021–22 NCAA Division I women's basketball season. The Tigers, led by twelfth-year head coach Robin Pingeton, played their home games at Mizzou Arena and competed as members of the Southeastern Conference (SEC).
The Tigers finished the season 9–13 (5–9 SEC) to finish in tenth place in the conference. The Tigers were invited to the 2021 Women's National Invitation Tournament where they lost to Fresno State in the first round.
| Name | Number | Pos. | Height | Year | Hometown | Notes | |
|---|---|---|---|---|---|---|---|
| Shannon Dufficy | 5 | F | 6'2" | RS Senior | Melbourne, Australia | Transferred to Oregon | |
| Nadia Green | 10 | G | 5'10" | Senior | Chicago, IL | Graduated | |
| Shug Dickson | 12 | G | 5'9" | RS Senior | St. Louis, MO | Transferred to Rutgers |
| Name | Number | Pos. | Height | Year | Hometown | Previous school | |
|---|---|---|---|---|---|---|---|
| Skylah Travis | 25 | F | 6'3" | RS Freshman | Old Dominion | ||
| [1] | |||||||
|-!colspan=9 style=| Exhibition|-!colspan=9 style=| Non-conference regular season|-!colspan=9 style=| SEC regular season|-!colspan=9 style=| SEC Tournament|-!colspan=9 style=| WNIT