| 2021–22 LEN Euro Cup | |
| League: | LEN Euro Cup |
| Sport: | Water Polo |
| Duration: | 30 September 2021–26 March 2022 |
| Finals Champ: |  Astralpool Sabadell (1st title) |
| Finals Runner-Up: |  Telimar Palermo |
| Seasonslist: | LEN Euro Cup |
| Seasonslistnames: | Euro Cup |
| Prevseason Link: | 2020–21 LEN Euro Cup |
| Prevseason Year: | 2020–21 |
| Nextseason Link: | 2022–23 LEN Euro Cup |
| Nextseason Year: | 2022–23 |
The 2021–22 LEN Euro Cup was the 30th edition of the second-tier European tournament for men's water polo clubs.
| width=25% | width=25% | width=25% | width=25% |
| width=25% |  Team Strasbourg | width=25% | GS Peristeri | width=25% | St Andreu | width=25% | UZSC Utrecht |
| width=25% | EN Tourcoing | width=25% |  Vasas Budapest | width=25% | Astralpool Sabadell | width=25% |  Shturm 2002 Ruza |
| width=25% | ASC Duisburg | width=25% | BVSC Zugló | width=25% |  Šabac | width=25% | Carouge Natation |
| width=25% | Ludwigsburg 08 | width=25% | CC Ortigia | width=25% | Vojvodina Novi Sad | ||
| width=25% | AEK Athens | width=25% | Telimar Palermo | width=25% | Solaris Šibenik |
The schedule of the competition is as follows.[1]
| Phase | Round | First leg | Second leg |
|---|---|---|---|
| Qualifying rounds | Qualification round I | 1–4 October 2021 | |
| Qualification round II | 8–10 October 2021 | ||
| Knockout phase | Quarterfinals | 27 October 2021 | 10 November 2021 |
| Semifinals | 12 January 2022 | 9 February 2022 | |
| Finals | 5 March 2022 | 26 March 2022 | |
The top two ranked sides from each group advance.[2]
The top two ranked sides from each group advance.[3] [4]
The four best teams from the Euro Cup qualifications and the four losing sides of the Champions League Qualification Round III have been paired in the quarter-finals.[5]
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