| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| PAF Korvpalli Meistriliiga1 | |
| Extra Information: | 1Sponsored league name, referring to PAF. |
| Season: | 2021–22 |
| Champions: | Pärnu Sadam |
| Runners Up: | Tartu Ülikool Maks & Moorits |
| Third Place: | Kalev/Cramo |
| Fourth Place: | TalTech/Optibet |
| Teams: | 8 |
| Duration: | 1 October 2021 – 24 April 2022 (regular season) 26 April 2022 – 26 May 2022 (Play-offs) |
| Top Seed: | BC Kalev/Cramo |
The 2021–22 Korvpalli Meistriliiga (KML) season, also known as PAF Korvpalli Meistriliiga for sponsorship reasons, was the 96th season of the top-tier basketball league in Estonia. The regular season began on 1 October 2021 and finished on 24 April 2022. The play-offs started on 26 April and finished on 26 May with Pärnu Sadam winning their first KML title.
| Team | Head coach | Captain | Kit manufacturer | Shirt sponsor | |
|---|---|---|---|---|---|
| AVIS UTILITAS Rapla |  Lluís Riera |  Sven Kaldre | Spalding | Hepa | |
| BC Kalev/Cramo | Roberts Štelmahers | Martin Dorbek | Nike | Unibet | |
| KK Viimsi/Sportland | Valdo Lips | Rain Veideman | Nike | Sportland | |
| Pärnu Sadam | Heiko Rannula | Mihkel Kirves | Nike | Betsafe | |
| Rakvere Tarvas | Martin Müürsepp | Sten Saaremäel | Spalding | Rakvere | |
| Tallinna Kalev | Brett Nõmm | Mario Paiste | Nike | Tallinn | |
| TalTech/OPTIBET | Alar Varrak | Tanel Sokk | Nike | ||
| Tartu Ülikool Maks & Moorits | Nikolajs Mazurs |  Adomas Drungilas | Spalding | Maks & Moorits |
In the regular season, teams played against each other once, with all results from the regular season of the 2021–22 Estonian-Latvian Basketball League being carried over.
See main article: 2022 KML Play-offs. Playoffs series are best-of-five. The first team to win three games wins the series.