| Club: | Partizan NIS Belgrade |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: |  Ostoja Mijailović |
| Manager: | Željko Obradović |
| League: | Serbian League |
| League Result: | Withdrew |
| League2: | ABA League |
| League2 Result: | 2nd |
| Cup1: | EuroCup |
| Cup1 Result: | Eightfinals |
| Cup2: | Serbian Cup |
| Cup2 Result: | Runner-up |
| Largest Win: | 109–49 vs Split (05 January 2022) |
| H Pattern B: | _kkpartizana |
| H Pattern S: | _kkpartizana |
| A Pattern B: | _kkpartizanh |
| A Pattern S: | _kkpartizanh |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
In the 2021–22 season, Partizan NIS Belgrade competed in the Serbian League, Radivoj Korać Cup, Adriatic League and EuroCup.
| Partizan NIS players out on loan | |||||
| Player | Position | Team | On loan since | ||
|---|---|---|---|---|---|
| Nikola Radovanović | SF | OKK Dunav (Two-way affiliate) | September 2021[1] | |
| Mihailo Petrović | PG | OKK Dunav (Two-way affiliate) | September 2021[2] | |
 | Trey Drechsel | SG |  BM Slam Stal Ostrów Wielkopolski | September 2021[3] | |
| Luka Tarlać | SF | OKK Dunav (Two-way affiliate) | September 2021[4] | |
 | Đorđije Jovanović | SG | OKK Dunav (Two-way affiliate) | September 2021 |
|}
|}
See main article: article and 2021–22 ABA League First Division.
See main article: article and 2021–22 EuroCup Basketball.
See main article: 2022 EuroCup Basketball Playoffs.
See main article: 2021–22 Radivoj Korać Cup.
See main article: 2022 Basketball League of Serbia playoffs and 2021–22 Basketball League of Serbia. On 9 June 2022, Partizan announced withdrawal from the 2022 Serbian League playoffs following numerous fan incidents in the 2022 ABA League Finals.[5] [6] Following their withdrawal, their semifinals opponent FMP Meridian advanced to the Finals.[7]
Adriatic League
MVP of the Round
Yam Madar – Round 5[8] Zach LeDay – Round 25 Zach LeDay – Semifinal Game 2 Kevin Punter – Semifinal Game 3 Kevin Punter – Final Game 3 Aleksa Avramović – Final Game 4 Kevin Punter – Final Game 5The Ideal Starting Five[9]
Coach of the Season[10]
EuroCup
MVP of the Round
Mathias Lessort – Round 13[11] Zach LeDay – Round 18[12]EuroCup Second Team
