| Club: | Eupen |
| Season: | 2021–22 |
| Owner: | Aspire Zone Foundation |
| Chairman: | Mishal bin Khalifa bin Nasser Al-Thani |
| Mgrtitle: | Manager |
| Manager: | Stefan Krämer |
| Stadium: | Kehrwegstadion |
| League: | Belgian First Division A |
| League Result: | 15th |
| Cup1: | Belgian Cup |
| Cup1 Result: | Semi-finals |
| League Topscorer: | Smail Prevljak (9) |
| Season Topscorer: | Smail Prevljak (16) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 77th season in the existence of K.A.S. Eupen and the club's sixth consecutive season in the top flight of Belgian football. In addition to the domestic league, Eupen participated in this season's edition of the Belgian Cup.
See main article: 2021–22 Belgian First Division A.
The league fixtures were announced on 8 June 2021.[1]
See main article: 2021–22 Belgian Cup.