| Mode: | Women's basketball |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | Howard Bison |
| Conference: | Mid-Eastern Athletic Conference |
| Short Conf: | MEAC |
| Record: | 21–10 |
| Conf Record: | 11–3 |
| Head Coach: | Ty Grace |
| Hc Year: | 7th |
| Asst Coach1: | Brian Davis |
| Ac1 Year: | 5th |
| Asst Coach2: | Donnie Stith |
| Ac2 Year: | 4th |
| Asst Coach3: | Jeanne-Marie Wilson |
| Ac3 Year: | 1st |
| Stadium: | Burr Gymnasium |
| Champion: | MEAC regular season co-champions MEAC tournament champions |
| Bowl: | NCAA tournament |
| Bowl Result: | first round |
The 2021–22 Howard Bison women's basketball team represented Howard University during the 2021–22 NCAA Division I women's basketball season. The Bison, led by seventh-year head coach Ty Grace, played their home games at Burr Gymnasium in Washington, D.C. as members of the Mid-Eastern Athletic Conference (MEAC).
They finished the season with a 21–10 overall record, 11–3 in MEAC play, to finish in a three-way tie for first place. As the first seed in the MEAC tournament, they defeated Delaware State, Maryland Eastern Shore and Norfolk State to win the championship. They received an automatic bid to the NCAA tournament, where they were one of the sixteenth seeds in the Greensboro Region. They defeated Incarnate Word in the First Four before losing to eventual champions South Carolina in the first round. The Bison lost 79–21, with their total being a new record for lowest team score in any D-I women's tournament game. The also trailed 44–4 at halftime, with their score also being the lowest in a half in tournament history.[1]
The Bison finished the season with a 15–4 overall record, 10–2 in MEAC play, to finish in first place in the North Division. As the first seed in the MEAC tournament, they defeated Norfolk State before losing to North Carolina A&T State in the Final. They were not invited to the NCAA tournament or the WNIT.
Source:[2]
|-!colspan=6 style=| Non-conference regular season|-!colspan=6 style=|MEAC regular season|-!colspan=6 style=| MEAC tournament|-!colspan=6 style=| NCAA tournament
See main article: 2021–22 NCAA Division I women's basketball rankings.
| Increase in ranking | |||
| Decrease in ranking | |||
| Not ranked previous week | |||
| (RV) | Received votes | ||
| (NR) | Not ranked and did not receive votes |
The Coaches Poll did not release a Week 2 poll and the AP poll did not release a poll after the NCAA tournament.