| Competition: | Handball-Bundesliga |
| Season: | 2021–22 |
| Dates: | 8 September 2021 – 12 June 2022 |
| Winners: | SC Magdeburg 2nd title |
| Relegated: | HBW Balingen-Weilstetten TuS Nettelstedt-Lübbecke |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | SC Magdeburg THW Kiel |
| Continentalcup2: | European League |
| Continentalcup2 Qualifiers: | Füchse Berlin SG Flensburg-Handewitt Frisch Auf Göppingen |
| League Topscorer: | Hans Lindberg (242 goals) |
| Matches: | 306 |
| Total Goals: | 16725 |
| Attendancecalc: | 953728 |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 Handball-Bundesliga (known as the Liqui Moly Handball-Bundesliga for sponsorship reasons) was the 57th season of the Handball-Bundesliga, Germany's premier handball league and the 45th season consisting of only one league. It ran from 8 September 2021 to 12 June 2022.[1]
SC Magdeburg won their second title.[2]
The following 18 clubs competed in the Handball-Bundesliga during the 2021–22 season:
| Team | Location | Arena | Capacity | |
|---|---|---|---|---|
| HBW Balingen-Weilstetten | Balingen | Sparkassen-Arena Porsche-Arena | 2,300 6,181 | |
| Bergischer HC | Wuppertal Solingen Düsseldorf | Uni-Halle Klingenhalle ISS Dome | 3,200 2,800 12,500 | |
| Füchse Berlin | Berlin | Max-Schmeling-Halle | 9,000 | |
| TV Bittenfeld | Stuttgart | Scharrena Stuttgart Porsche-Arena | 2,251 6,211 | |
| HC Erlangen | Nuremberg | Arena Nürnberger Versicherung | 8,308 | |
| SG Flensburg-Handewitt | Flensburg | Flens-Arena | 6,300 | |
| Frisch Auf Göppingen | Göppingen | EWS Arena | 5,600 | |
| HSV Hamburg | Hamburg | Alsterdorfer Sporthalle | 7,000 | |
| TSV Hannover-Burgdorf | Hanover | ZAG-Arena Swiss Life Hall | 9,850 4,460 | |
| THW Kiel | Kiel | Wunderino Arena | 10,285 | |
| SC DHfK Leipzig | Leipzig | Arena Leipzig | 6,327 | |
| TBV Lemgo | Lemgo | Lipperlandhalle | 4,790 | |
| TuS Nettelstedt-Lübbecke | Lübbecke | Merkur Arena | 3,300 | |
| SC Magdeburg | Magdeburg | GETEC Arena | 6,600 | |
| MT Melsungen | Melsungen | Rothenbach-Halle | 4,300 | |
| GWD Minden | Minden | Kampa-Halle | 4,059 | |
| Rhein-Neckar Löwen | Mannheim | SAP Arena | 13,200 | |
| HSG Wetzlar | Wetzlar | Rittal Arena Wetzlar | 4,421 |
| Rank | Player | Club | Goals[3] | Shots | ||
|---|---|---|---|---|---|---|
| 1 | Hans Lindberg | Füchse Berlin | 242 | 288 | 84 | |
| 2 |  Ómar Ingi Magnússon | SC Magdeburg | 237 | 339 | 70 | |
| 3 | Bjarki Már Elísson | TBV Lemgo | 234 | 319 | 73 | |
| 4 | Casper Ulrich Mortensen | HSV Hamburg | 206 | 288 | 72 | |
| 5 |  Niclas Ekberg | THW Kiel | 189 | 245 | 77 | |
| 6 | Marcel Schiller | Frisch Auf Göppingen | 186 | 259 | 72 | |
| 7 |  Vladan Lipovina | HBW Balingen-Weilstetten | 177 | 345 | 51 | |
| 8 | Simon Jeppsson | HC Erlangen | 176 | 302 | 58 | |
| 9 | Tom Skroblien | TuS Nettelstedt-Lübbecke | 172 | 251 | 69 | |
| 10 | Jóhan Hansen | TSV Hannover-Burgdorf | 162 | 250 | 65 |