| Competition: | Greek A Division |
| Season: | 2021–22 |
| Winners: | PAOK 17th title |
| Relegated: | Agia Paraskevi Agrotikos Asteras AEK Messolonghiou Giannena Doxa 2016 Feidon Argous |
| Continentalcup1: | Women's Champions League |
| Continentalcup1 Qualifiers: | PAOK |
| League Topscorer: | Esse Akida (18 goals) |
| Biggest Home Win: | PAOK 11–0 Agrotikos Asteras |
| Biggest Away Win: | Agrotikos Asteras 0–9 PAOK |
| Highest Scoring: | PAOK 11–0 Agrotikos Asteras |
| Longest Wins: | 18 games PAOK |
| Longest Unbeaten: | 20 games PAOK |
| Longest Winless: | 16 games Agia Paraskevi Feidon Argous |
| Longest Losses: | 12 games Agrotikos Asteras |
| Matches: | 152 |
| Total Goals: | 483 |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| Updated: | 1 September 2023 |
The 2021–22 Greek A Division is the 33rd season of the women's football top-level league in Greece. PAOK won their 8th consecutive title and their 17th overall.
The Greek A Division for the 2021–22 season will be held in 2 groupsof 9 teams, 18 teams in total. The separation of the teams into these groups will take place based on geographical criteria.
The championship will be held in two phases. In the 1st phase, the teams of each group will compete in two rounds. In the 2nd phase, a play-off round will be held to determine the champion.
The first two teams of each group will form a group of 4 teams and will compete in Phase B.The order of the games will be determined after a draw. No matches will be held between the teams that competed in the same group in Phase A. The matches of Phase B will be in two rounds and a total of 8 matches will be played in 4 matchdays.
After the end of Phase A, for the 2022–23 season, the teams whichoccupy the last 3 positions in each group will be relegated to the Greek B Division, a total of 6 teams.[1]
| Team | City | Stadium | Capacity |
|---|---|---|---|
| Agrotikos Asteras | 2,267 | ||
| Aris Thessaloniki | Agios Vasileios Stadium | ||
| Iraklis Adrianis Stadium | 1,000 | ||
| 6,000 | |||
| EPFCA Stadium Ioannina | |||
| Kastoria | 8,000 | ||
| AEL | Neapoli Stadium | 2,000 | |
| PAOK | |||
| 15,000 | |||
| Team | City | Stadium | Capacity |
|---|---|---|---|
| Municipal Football Stadium of Avlida | 2,000 | ||
| Agia Paraskevi | Municipal Stadium of Agia Paraskevi | 2,800 | |
| Messolonghi Municipal Stadium | 3,500 | ||
| Nikos Kazantzakis Stadium | 1,000 | ||
| Sohora Municipal Stadium | |||
| Odysseas Moschato | 900 | ||
| OFI Crete | Krousonas Municipal Stadium | 1,500 | |
| Olympiada Imittos | Hymettus Municipal Stadium | 1,000 | |
| Kiveri Stadium | 100 | ||
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Esse Akida | PAOK | 17 |
| 2 |  Kiyani Johnson | Ergotelis | 13 |
| 3 |  Gisela Arrieta | Asteras Rethymnou | 10 |
| Maria Mpasouri | PAOK | ||
| 4 |  Sasha Strubelova | AEL | 9 |
| Aqsa Mushtaq | Avantes Chalkida | ||
| Maria Mitkou | PAOK | ||
| Konstantina Kostopoulou | Trikala | ||
| 5 |  Nikolina Musto | AEL | 8 |
| Trista Seara | |||
| Ilektra Plyta | Avantes Chalkida | ||
 Gerli Israel | OFI | ||