| Club: | Granada CF |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: | Rentao Yi |
| Mgrtitle: | Head coach |
| Manager: | Robert Moreno (until 6 March) Rubén Torrecilla (caretaker, from 6 March to 18 April) Aitor Karanka (from 18 April) |
| Stadium: | Nuevo Los Cármenes |
| League: | La Liga |
| League Result: | 18th (relegated) |
| Cup1: | Copa del Rey |
| Cup1 Result: | Second round |
| League Topscorer: | Jorge Molina (10) |
| Season Topscorer: | Jorge Molina (12) |
| Largest Win: | Mallorca 2–6 Granada |
| Largest Loss: | Rayo Vallecano 4–0 Granada |
| Pattern La1: | _acp17h |
| Pattern B1: | _granada2122h |
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| Pattern La2: | _nikestrike3w |
| Pattern B2: | _nikestrike3w |
| Pattern Ra2: | _nikestrike3w |
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| Pattern B3: | _nikechallenge3g |
| Leftarm3: | 008000 |
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| Shorts3: | 990000 |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 88th season in the existence of Granada CF and the club's third consecutive season in the top flight of Spanish football. In addition to the domestic league, Granada participated in this season's edition of the Copa del Rey.
See main article: Club Recreativo Granada.
| Date | Player | From | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [2] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [3] | ||
| 16 July 2021 | Transfer | Free | [4] | ||
| Date | Player | To | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [5] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [6] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [7] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [8] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [9] | ||
| 1 July 2021 | Transfer | Free | [10] | ||
| 1 July 2021 | Transfer | €500k | [11] | ||
See main article: 2021–22 La Liga.
The league fixtures were announced on 30 June 2021.[12] [13]
See main article: 2021–22 Copa del Rey.
| Rank | Player | La Liga | Copa del Rey | Total | |
|---|---|---|---|---|---|
| 1 |  Jorge Molina | 10 | 2 | 12 | |
| 2 |  Luis Suárez | 8 | 0 | 8 | |
| 3 | Antonio Puertas | 6 | 1 | 7 | |
| 4 |  Darwin Machís | 4 | 0 | 4 | |
| 5 | Adrián Butzke | 0 | 3 | 3 | |
| Luis Milla | 3 | 0 | 3 | ||
| 7 | |||||
| Álex Collado | 2 | 0 | 2 | ||
| Germán Sánchez | 2 | 0 | 2 | ||
| Sergio Escudero | 2 | 0 | 2 | ||
| 10 | |||||
| Santiago Arias | 1 | 0 | 1 | ||
| Carlos Bacca | 0 | 1 | 1 | ||
| Víctor Díaz | 1 | 0 | 1 | ||
| Domingos Duarte | 1 | 0 | 1 | ||
| Ángel Montoro | 1 | 0 | 1 | ||
| Rubén Rochina | 1 | 0 | 1 | ||
 Myrto Uzuni | 1 | 0 | 1 | ||
| align=center colspan=2 | Own goals | 1 | 0 | 1 | |
| Total | 44 | 7 | 45 | ||