| Club: | Getafe CF |
| Season: | 2021–22 |
| Owner: | Ángel Torres |
| Chrtitle: | President |
| Chairman: | Ángel Torres |
| Mgrtitle: | Head coach |
| Manager: | Míchel (until 4 October) Quique Sánchez Flores (from 6 October) |
| Stadium: | Coliseum Alfonso Pérez |
| League: | La Liga |
| League Result: | 15th |
| Cup1: | Copa del Rey |
| Cup1 Result: | Second round |
| League Topscorer: | Enes Ünal (16) |
| Season Topscorer: | Enes Ünal (16) |
| Pattern Name1: | Home |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 39th season in the existence of Getafe CF and the club's fifth consecutive season in the top flight of Spanish football. In addition to the domestic league, Getafe participated in this season's edition of the Copa del Rey.
See main article: Getafe CF B.
| Date | Player | From | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [2] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [3] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [4] | ||
| 5 July 2021 | align=center colspan=2 | Loan | [5] | ||
| 5 July 2021 | align=center colspan=2 | Loan | [6] | ||
| 6 July 2021 | Transfer | Undisclosed | [7] | ||
| 10 July 2021 | align=center colspan=2 | €5,000,000 | [8] | ||
| 2 August 2021 | align=center colspan=2 | Loan | [9] | ||
| Date | Player | To | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [10] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [11] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [12] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [13] | ||
| 30 June 2021 | Transfer | Undisclosed | [14] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [15] | ||
| 2 July 2021 | Transfer | Free | [16] | ||
See main article: 2021–22 La Liga.
The league fixtures were announced on 30 June 2021.[17] [18]
See main article: 2021–22 Copa del Rey.
| Rank | Player | La Liga | Copa del Rey | Total | |
|---|---|---|---|---|---|
| 1 |  Enes Ünal | 15 | 0 | 15 | |
| 2 |  Borja Mayoral | 6 | 0 | 6 | |
| 3 | Jaime Mata | 1 | 3 | 4 | |
| Sandro Ramírez | 3 | 1 | 4 | ||
| 5 | Carles Aleñá | 1 | 0 | 1 | |
| Jorge Cuenca | 1 | 0 | 1 | ||
| Nemanja Maksimović | 1 | 0 | 1 | ||
| Stefan Mitrović | 1 | 0 | 1 | ||
| Mathías Olivera | 1 | 0 | 1 | ||
| Darío Poveda | 0 | 1 | 1 | ||
| align=center colspan=2 | Own goals | 0 | 0 | 0 | |
| Total | 31 | 5 | 36 | ||