| FA Vase | |
| Year: | 2021–22 |
| Other Titles: | Football Association Vase |
| Country: | England Wales Jersey Isle of Man |
| Dates: | Qualifying: Competition Proper: 22 October 2021 – 22 May 2022 |
| Num Teams: | Qualifying: 567 Competition Proper: 51 (+ 182 from Qualifying) Total: 618 |
| Defending Champions: | Warrington Rylands |
| Champions: | Newport Pagnell Town |
| Count: | 1 |
| Runner-Up: | Littlehampton Town |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 FA Vase (Known for sponsorship reasons as the Buildbase FA Vase) was the 48th season of the FA Vase, an annual football competition for teams playing in Levels 9 and 10 (steps 5 & 6) of the English National League System. The competition is played with two qualifying rounds followed by six proper rounds, semi-finals, and the final played at Wembley Stadium. All ties this season were played to a finish on the day. For this season there were no replays in any of the rounds to minimise fixture congestion due to late start of the football season brought about by the COVID-19 pandemic. If games finished level after 90 minutes, the match was decided by penalties to find the winner of the tie, apart from the Final where there were 30 minutes extra time (15 minutes each way) followed by penalties if still level after the extra time period.[1]
| scope=col style"width:700px" | Round | scope=col style"width:725px" | Main date | scope=col style"width:175px" | Number of fixtures | scope=col style"width:175px" | Clubs remaining | scope=col style"width:125px" | New entries this round | scope=col style"width:125px" | Prize money winners | scope=col style"width:1125px" | Prize money losers |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Saturday, 11 September 2021 | 203 | 618 → 415 | 406 | £525 | £175 | ||||||||
| Saturday, 25 September 2021 | 182 | 415 → 233 | 161 | £675 | £225 | ||||||||
| Saturday, 23 October 2021 | 105 | 233 → 128 | 28 | £750 | £250 | ||||||||
| Saturday, 20 November 2021 | 64 | 128 → 64 | 23 | £825 | £275 | ||||||||
| Saturday, 11 December 2021 | 32 | 64 → 32 | None | £1,050 | £350 | ||||||||
| Saturday, 15 January 2022 | 16 | 32 → 16 | None | £1,875 | £625 | ||||||||
| Saturday, 12 February 2022 | 8 | 16 → 8 | None | £2,250 | £750 | ||||||||
| Saturday, 12 March 2022 | 4 | 8 → 4 | None | £4,125 | £1,375 | ||||||||
| Saturday, 2 April 2022 | 2 | 4 → 2 | None | £5,475 | £1,825 | ||||||||
| Sunday, 22 May 2022 | 1 | 2 → 1 | None | £30,000 | £15,000 |
The draw was made on 9 July 2021.[2]
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| Friday, 10 September 2021 | ||||
| 7 | Washington (10) | 0–5 | Thornaby (9) | 107 |
| 131 | Eversley & California (10) | 3–0 | Virginia Water (9) | 168 |
| 90 | St Margaretsbury (9) | 0–2 | Benfleet (10) | 75 |
| 144 | Canterbury City (9) | 5–0 | FC Elmstead (10) | |
| 36 | FC Humber United (10) | 1–4 | Parkgate (10) | 116 |
| 41 | Handsworth (9) | 1–2 | Golcar United (10) | 278 |
| Saturday, 11 September 2021 | ||||
| 56 | Uttoxeter Town (9) | 2–0 | Littleton (10) | |
| 110 | Burnham (9) | 6–1 | Bedford (10) | 86 |
| 1 | Padiham (9) | 0–4 | North Shields (9) | 243 |
| 2 | Chester-Le-Street Town (10) | 1–1 (3–1 p) | Jarrow (10) | 122 |
| 3 | Willington (10) | 3–2 | Tow Law Town (10) | 110 |
| 4 | West Allotment Celtic (9) | 5–5 (4–3 p) | Steeton (10) | 84 |
| 5 | Carlisle City (10) | 1–0 | Guisborough Town (9) | 146 |
| 6 | Whitley Bay (9) | 3–4 | Billingham Synthonia (10) | 422 |
| 8 | Squires Gate (9) | 1–1 (3–4 p) | Garforth Town (9) | 41 |
| 9 | Newcastle University (10) | 1–1 (3–4 p) | Heaton Stannington (10) | 88 |
| 10 | Barnoldswick Town (9) | 3–3 (9–8 p) | AFC Blackpool (10) | 253 |
| 11 | Easington Colliery (10) | 2–1 | Redcar Athletic (9) | 85 |
| 12 | Campion (10) | 3–3 (2–3 p) | Newton Aycliffe (9) | 100 |
| 13 | Crook Town (9) | 0–2 | Eccleshill United (9) | 204 |
| 14 | Sunderland West End (10) | 2–3 | Cleator Moor Celtic (10) | 34 |
| 15 | Sunderland RCA (9) | 1–2 | Redcar Town (10) | 87 |
| 16 | Bishop Auckland (9) | 2–2 (15–14 p) | Ryton & Crawcrook Albion (10) | 268 |
| 17 | Ilkley Town (10) | 1–2 | Penrith (9) | 121 |
| 18 | Newcastle Benfield (9) | 3–2 | Ashington (9) | 192 |
| 19 | Silsden (9) | 1–2 | Albion Sports (9) | |
| 20 | Litherland REMYCA (9) | 0–6 | Wythenshawe Town (9) | 68 |
| 21 | Avro (9) | 2–1 | AFC Darwen (10) | 85 |
| 22 | AFC Liverpool (9) | 5–3 | Charnock Richard (9) | 114 |
| 23 | Athersley Recreation (9) | 1–5 | Chadderton (10) | 121 |
| 24 | Brigg Town (10) | 3–2 | Cammell Laird 1907 (10) | 269 |
| 25 | Runcorn Town (9) | 4–1 | Ashton Town (10) | 114 |
| 26 | FC St Helens (10) | South Liverpool (10) | ||
| Walkover for South Liverpool – FC St Helens not accepted into the competition | ||||
| 27 | Burscough (9) | 2–1 | Hallam (10) | 106 |
| 28 | New Mills (10) | 1–1 (6–5 p) | Armthorpe Welfare (10) | 120 |
| 29 | Bacup Borough (10) | 1–0 | Penistone Church (9) | 122 |
| 30 | St Helens Town (10) | 0–4 | Cheadle Heath Nomads (10) | 38 |
| 31 | West Didsbury & Chorlton (10) | 3–2 | Nostell MW (10) | |
| 32 | Northwich Victoria (9) | 1–2 | Bury AFC (10) | 507 |
| 33 | Skelmersdale United (9) | 9–1 | Retford (10) | 145 |
| 34 | Maltby Main (9) | 1–1 (5–4 p) | Glasshoughton Welfare (10) | 75 |
| 35 | Swallownest (10) | 3–1 | Bottesford Town (9) | |
| 37 | Selby Town (10) | 5–2 | Hemsworth Miners Welfare (9) | 302 |
| 38 | Winterton Rangers (9) | 3–2 | Macclesfield (9) | |
| 39 | Dronfield Town (10) | 1–0 | Barnton (10) | 92 |
| 42 | Cheadle Town (10) | 0–1 | Irlam (9) | 75 |
| 43 | Abbey Hey (10) | 1–0 | Ashton Athletic (9) | 72 |
| 44 | Shifnal Town (9) | 5–1 | Smethwick Rangers (10) | |
| 46 | Brocton (10) | 1–5 | Boldmere St. Michaels (9) | 89 |
| 47 | Winsford United (9) | 3–1 | Stapenhill (10) | 145 |
| 48 | Hinckley LR (9) | 3–0 | Cradley Town (10) | |
| 49 | Shawbury United (10) | 0–4 | Romulus (9) | |
| 50 | Lichfield City (9) | 2–1 | FC Stratford (10) | |
| 51 | Haughmond (9) | 2–3 | Ashby Ivanhoe (10) | |
| 52 | Wem Town (10) | Bilston Town (10) | ||
| Walkover for Bilston Town – Wem Town not accepted into the competition | ||||
| 53 | Bewdley Town (9) | 2–2 (7–6 p) | Hereford Lads Club (9) | |
| 54 | Wellington (10) | Nuneaton Griff (10) | ||
| Nuneaton Griff awarded a walkover due to Wellington withdrawing from the Hellenic Football League.[3] | ||||
| 55 | Stone Old Alleynians (9) | 2–3 | Heather St John's (9) | |
| 57 | Atherstone Town (10) | 2–1 | Abbey Hulton United (10) | 282 |
| 58 | AFC Bridgnorth (10) | 2–1 | Rocester (10) | |
| 59 | Studley (10) | 2–0 | Paget Rangers (10) | |
| 60 | Whitchurch Alport (9) | 3–0 | Tividale (9) | |
| 61 | Coventry Copsewood (10) | 2–8 | Rugby Town (9) | |
| 62 | Gresley Rovers (9) | 7–0 | Dudley Sports (10) | |
| 63 | Stafford Town (10) | Eccleshall (10) | ||
| Stafford Town awarded a walkover due to Eccleshall withdrawing from the competition.[4] | ||||
| 64 | St Martins (10) | 0–18 | Hinckley AFC (10) | 56 |
| 65 | Bourne Town (10) | 1–2 | Belper United (10) | |
| 66 | Clipstone (10) | 1–1 (4–5 p) | St Andrews (10) | 59 |
| 67 | Teversal (10) | 0–2 | Eastwood Community (9) | 81 |
| 68 | Saffron Dynamo (10) | 1–1 (1–4 p) | Quorn (9) | |
| 69 | Melton Town (9) | P–P | West Bridgford (10) | |
| 70 | Sherwood Colliery (9) | 1–0 | Borrowash Victoria (10) | 115 |
| 71 | Selston (9) | 2–1 | Barrow Town (10) | |
| 72 | Dunkirk (10) | 3–0 | AFC Mansfield (9) | |
| 73 | Leicester Nirvana (9) | 4–1 | Clifton All Whites (10) | |
| 74 | Birstall United (10) | 2–2 (6–5 p) | Kirby Muxloe (10) | |
| 75 | Hucknall Town (10) | 1–3 | Gedling MW (10) | |
| 76 | Ingles (10) | 4–1 | Blackstones (10) | |
| 77 | Boston Town (9) | 4–1 | Lutterworth Athletic (10) | |
| 78 | Rainworth MW (10) | 0–2 | Heanor Town (9) | 99 |
| 79 | Deeping Rangers (9) | 3–0 | Holwell Sports (10) | |
| 80 | Debenham LC (10) | 1–1 (4–2 p) | Peterborough Northern Star (9) | |
| 81 | Eynesbury Rovers (9) | 2–0 | Huntingdon Town (10) | |
| 82 | Wisbech St Mary (10) | 0–6 | Great Yarmouth Town (10) | |
| 83 | Godmanchester Rovers (9) | 6–1 | FC Parson Drove (10) | |
| 84 | Walsham-le-Willows (9) | A–A | March Town United (9) | |
| Match abandoned tied 0–0, due to a supporter requiring an ambulance. | ||||
| 86 | Brimsdown (10) | 0–1 | Barkingside (10) | |
| 87 | Whitton United (9) | 4–3 | Enfield Borough (10) | |
| 88 | Takeley (9) | 2–0 | Frenford (10) | 85 |
| 89 | Long Melford (9) | 3–0 | Little Oakley (9) | |
| 91 | Newbury Forest (10) | 1–0 | Haverhill Borough (10) | |
| 92 | Halstead Town (10) | 1–2 | Potton United (9) | |
| 94 | Walthamstow (9) | 0–0 (3–4 p) | Hadleigh United (9) | 84 |
| 95 | Woodbridge Town (9) | 1–1 (4–5 p) | Woodford Town (9) | |
| 96 | Hoddesdon Town (9) | 5–2 | FC Clacton (9) | 83 |
| 97 | Biggleswade United (9) | 0–8 | Southend Manor (9) | |
| 98 | Maccabi London Lions (10) | 2–1 | St. Panteleimon (9) | |
| 99 | Stotfold (10) | 1–5 | White Ensign (9) | 165 |
| 101 | Park View (10) | 2–2 (1–3 p) | Sawbridgeworth Town (9) | |
| 102 | Harwich & Parkeston (10) | 1–2 | Ipswich Wanderers (10) | |
| 103 | Brantham Athletic (9) | 1–2 | Holland (10) | |
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| 104 | Sudbury Sports (10) | May & Baker (10) | |||
| Walkover for May & Baker – Sudbury Sports not accepted into the competition | |||||
| 105 | Buckhurst Hill (10) | 3–0 | Enfield (9) | ||
| 106 | Windsor (9) | 3–0 | Kensington & Ealing Borough (10) | ||
| 107 | British Airways (10) | 2–2 (5–4 p) | Dunstable Town (9) | ||
| 109 | Cogenhoe United (9) | 2–3 | Harefield United (9) | ||
| 111 | Amersham Town (10) | 2–3 | Winslow United (10) | 82 | |
| 113 | Holmer Green (9) | 2–0 | Spelthorne Sports (9) | 52 | |
| 114 | Buckingham Athletic (10) | 4–2 | Rushden & Higham United (10) | 65 | |
| 115 | Long Buckby (9) | 2–2 (2–4 p) | Tring Athletic (9) | 69 | |
| 116 | Arlesey Town (9) | 4–4 (3–4 p) | FC Deportivo Galicia (10) | 80 | |
| 117 | Risborough Rangers (9) | 3–2 | Edgware Town (9) | 103 | |
| 118 | London Colney (9) | 1–1 (4–3 p) | Leverstock Green (9) | 48 | |
| 119 | Hilltop (10) | 4–2 | Langley (10) | ||
| 120 | Ardley United (9) | 5–0 | Burton Park Wanderers (10) | 62 | |
| 121 | Egham Town (9) | 1–1 (11–10 p) | Crawley Green (9) | 47 | |
| 122 | Broadfields United (9) | 1–0 | Holyport (9) | 40 | |
| 123 | Aylesbury Vale Dynamos (9) | 3–1 | London Tigers (10) | 88 | |
| 124 | Wembley (9) | 5–1 | Oxhey Jets (9) | ||
| 125 | Camberley Town (9) | 1–1 (4–5 p) | Long Crendon (10) | ||
| 126 | Sheerwater (9) | 4–1 | Roman Glass St George (9) | ||
| 127 | Shortwood United (10) | 4–2 | Cove (10) | 48 | |
| 128 | Longlevens (10) | 3–2 | Fairford Town (9) | 84 | |
| 129 | Wokingham & Emmbrook (9) | 4–0 | Moreton Rangers (10) | ||
| 130 | Frimley Green (9) | 3–0 | Shrivenham (9) | ||
| 132 | Berks County (10) | 3–1 | Newent Town (10) | ||
| 133 | Hengrove Athletic (10) | 0–2 | Ascot United (9) | 70 | |
| 134 | Stonehouse Town (10) | 0–2 | Ashton & Backwell United (9) | 74 | |
| 135 | Brislington (9) | 4–0 | Fleet Town (9) | 75 | |
| 136 | Almondsbury (10) | 1–2 | Cheltenham Saracens (10) | 34 | |
| 137 | Royal Wootton Bassett Town (9) | 1–0 | Knaphill (10) | 78 | |
| 138 | Bishop's Cleeve (9) | 4–1 | Thornbury Town (9) | 94 | |
| 139 | Reading City (9) | 1–2 | Cribbs (9) | 30 | |
| 140 | Malmesbury Victoria (10) | 2–4 | Tuffley Rovers (9) | ||
| 141 | Clanfield (10) | 2–3 | Wallingford Town (10) | ||
| 142 | Lydney Town (9) | 3–3 (4–5 p) | Hallen (9) | ||
| 143 | Rochester United (10) | 3–2 | Hollands & Blair (9) | ||
| 145 | Staplehurst Monarchs (10) | 3–2 | Sporting Bengal United (9) | 122 | |
| 146 | Broadbridge Heath (9) | 3–3 (5–6 p) | Croydon (10) | ||
| 147 | Erith Town (9) | 2–0 | Sporting Club Thamesmead (10) | 50 | |
| 148 | AFC Uckfield Town (9) | 2–3 | Colliers Wood United (9) | ||
| 149 | Westside (10) | 1–2 | Snodland Town (10) | 38 | |
| 150 | Tunbridge Wells (9) | 1–1 (4–3 p) | Roffey (10) | ||
| 151 | Abbey Rangers (9) | 4–0 | Horsham YMCA (9) | ||
| 152 | Crawley Down Gatwick (9) | 3–1 | Lewisham Borough (10) | ||
| 153 | Eastbourne United (9) | 0–3 | Bridon Ropes (10) | ||
| 155 | Raynes Park Vale (9) | 3–1 | Steyning Town Community (9) | ||
| 156 | Molesey (9) | 0–2 | Shoreham (10) | ||
| 157 | Banstead Athletic (9) | 0–1 | Horley Town (9) | ||
| 158 | Lordswood (9) | 4–0 | Storrington Community (10) | 60 | |
| 159 | Eastbourne Town (9) | 0–1 | Sheppey United (9) | 238 | |
| 160 | Sutton Athletic (10) | 4–2 | Newhaven (9) | 67 | |
| 161 | East Preston (9) | 0–5 | Redhill (9) | ||
| 162 | Lingfield (9) | 1–2 | Erith & Belvedere (9) | ||
| 163 | Larkfield & New Hythe Wanderers (10) | 2–3 | Epsom & Ewell (10) | 187 | |
| 164 | Seaford Town (10) | 1–1 (4–2 p) | Peacehaven & Telscombe (9) | ||
| 165 | Billingshurst (10) | 0–3 | Forest Hill Park (10) | ||
| 166 | Rusthall (9) | 0–2 | Crowborough Athletic (9) | ||
| 167 | Balham (9) | 1–2 | Tower Hamlets (9) | ||
| 168 | Bearsted (9) | 0–1 | Fisher (9) | ||
| 170 | Oakwood (10) | 3–4 | Welling Town (9) | ||
| 171 | Loxwood (9) | 1–0 | Faversham Strike Force (10) | ||
| 172 | K Sports (9) | 0–5 | Beckenham Town (9) | 49 | |
| 173 | Stansfeld (10) | 3–1 | Bagshot (10) | ||
| 174 | Horndean (9) | 9–0 | Hamble Club (9) | 63 | |
| 175 | Wick (10) | 0–0 (1–4 p) | Alton (9) | ||
| 176 | Radstock Town (10) | 0–1 | Arundel (10) | 70 | |
| 177 | Westbury United (9) | 1–4 | Alresford Town (9) | 58 | |
| 178 | AFC Stoneham (9) | 4–0 | Portland United (9) | 59 | |
| 179 | Folland Sports (10) | 0–1 | Corsham Town (9) | 60 | |
| 180 | Millbrook (10) | 0–2 | Shaftesbury (9) | 76 | |
| 181 | Cowes Sports (9) | 3–4 | Bournemouth (9) | 122 | |
| 182 | Amesbury Town (9) | 1–4 | Andover New Street (10) | 62 | |
| 183 | Baffins Milton Rovers (9) | 1–3 | Andover Town (10) | 105 | |
| 184 | Selsey (10) | 0–1 | Pagham (9) | ||
| 185 | Bradford Town (9) | 3–0 | Wincanton Town (10) | 84 | |
| 186 | Calne Town (9) | 1–4 | Whitchurch United (10) | 94 | |
| 187 | Sherborne Town (10) | 5–3 | Verwood Town (10) | ||
| 188 | Moneyfields (9) | 4–0 | Totton & Eling (10) | 86 | |
| 189 | Ash United (10) | 2–0 | Hythe & Dibden (9) | 50 | |
| 190 | Devizes Town (10) | 0–10 | Badshot Lea (9) | 92 | |
| 191 | Petersfield Town (10) | 0–3 | Bashley (9) | 113 | |
| 192 | Farnham Town (9) | 4–0 | Warminster Town (10) | ||
| 193 | AFC Portchester (9) | 4–0 | Romsey Town (10) | 177 | |
| 194 | Ringwood Town (10) | 2–0 | Bridport (9) | 44 | |
| 195 | Godolphin Atlantic (10) | 1–3 | Bovey Tracey (10) | ||
| 196 | Saltash United (9) | 3–1 | Cullompton Rangers (10) | ||
| 197 | Exmouth Town (9) | 0–1 | Shepton Mallet (9) | 244 | |
| 198 | Torpoint Athletic (10) | 1–0 | Callington Town (10) | ||
| 199 | Wadebridge Town (10) | 2–1 | AFC St Austell (10) | ||
| 200 | Bodmin Town (10) | 3–3 (5–3 p) | Crediton United (10) | ||
| 201 | Ilfracombe Town (9) | 0–2 | Bishop Sutton (10) | 78 | |
| 202 | Elburton Villa (10) | 0–4 | Welton Rovers (10) | ||
| 203 | Torrington (10) | 1–1 (2–3 p) | Bishops Lydeard (10) | ||
| 108 | Chalvey Sports (10) | 0–2 | Rothwell Corinthians (9) | ||
| 154 | Greenways (10) | 2–2 (5–4 p) | Lydd Town (10) | ||
| Sunday, 12 September 2021 | |||||
| 169 | Tooting Bec (10) | 0–3 | Jersey Bulls (9) | 163 | |
| 40 | Worsbrough Bridge Athletic (10) | 1–2 | Maine Road (10) | 226 | |
| 45 | Dudley Town (10) | 2–0 | Alsager Town (10) | 196 | |
| 85 | UEA (10) | 1–2 | Swaffham Town (9) | ||
| 93 | Coggeshall United (10) | 1–3 | Glebe (9) | ||
| 100 | Hackney Wick (10) | 1–4 | New Salamis (9) | ||
| 112 | Irchester United (10) | 1–5 | Hillingdon Borough (10) | ||
| Tuesday, 14 September 2021 | |||||
| 69 | Melton Town (9) | 3–0 | West Bridgford (10) | ||
| Match played at West Bridgford. | |||||
| 84 | Walsham-le-Willows (9) | 5–2 | March Town United (9) | ||
The draw was also made on 9 July 2021.[2]
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| 86 | Wivenhoe Town (10) | 2–1 | Stanway Rovers (9) | 138 |
| 87 | Whitton United (9) | 5–1 | Wormley Rovers (10) | 31 |
| 89 | Cornard United (10) | 3–2 | Barkingside (10) | 35 |
| 91 | Langford (10) | 1–4 | Ilford (9) | 61 |
| 92 | Burnham Ramblers (10) | 3–4 | Long Melford (9) | 45 |
| 93 | Haverhill Rovers (9) | 2–2 (4–5 p) | London Lions (10) | 70 |
| 95 | Northampton Sileby Rangers (10) | 3–4 | Buckingham Athletic (10) | 47 |
| 96 | AFC Hayes (10) | 0–3 | Risborough Rangers (9) | 91 |
| 97 | Wembley (9) | 0–0 (4–5 p) | Holmer Green (9) | 47 |
| 98 | FC Deportivo Galicia (10) | 1–4 | Tring Athletic (9) | 39 |
| 99 | Egham Town (9) | 3–2 | Northampton ON Chenecks (9) | |
| 101 | Hillingdon Borough (10) | 1–1 (5–3 p) | Bugbrooke St Michaels (9) | |
| 103 | Southall (9) | 5–1 | CB Hounslow United (9) | |
| 104 | British Airways (10) | 3–1 | Desborough Town (9) | |
| 105 | Burnham (9) | 3–0 | Aylesbury Vale Dynamos (9) | 89 |
| 106 | Wellingborough Whitworth (10) | 5–1 | Windsor (9) | 65 |
| 107 | Ardley United (9) | 5–0 | Rothwell Corinthians (9) | 35 |
| 108 | Newport Pagnell Town (9) | 1–0 | Harpenden Town (9) | 141 |
| 109 | Penn & Tylers Green (10) | 1–1 (3–4 p) | Harefield United (9) | 37 |
| 110 | Easington Sports (9) | 0–2 | London Colney (9) | 63 |
| 111 | Frimley Green (9) | 3–1 | AFC Aldermaston (10) | |
| 112 | Tadley Calleva (9) | 1–4 | Ascot United (9) | |
| 113 | Bitton (9) | 3–1 | Cheltenham Saracens (10) | |
| 114 | Abingdon United (10) | 1–10 | Berks County (10) | 44 |
| 115 | Brislington (9) | 1–2 | Ashton & Backwell United (9) | 70 |
| 116 | Tuffley Rovers (9) | 3–2 | Fleet Spurs (10) | 82 |
| 117 | Bishop's Cleeve (9) | 4–4 (3–4 p) | Wallingford Town (10) | 103 |
| 119 | Bristol Telephones (10) | 1–6 | Chipping Sodbury Town (9) | 23 |
| 121 | Sheerwater (9) | 1–0 | Tytherington Rocks (10) | |
| 122 | Wokingham & Emmbrook (9) | 1–1 (5–4 p) | Hallen (9) | |
| 123 | Keynsham Town (9) | 4–1 | Long Crendon (10) | 78 |
| 124 | Cribbs (9) | 1–1 (5–4 p) | Shortwood United (10) | 69 |
| 125 | Milton United (10) | 6–0 | Woodley United (10) | 62 |
| 127 | Portishead Town (10) | 1–3 | Royal Wootton Bassett Town (9) | 67 |
| 128 | Raynes Park Vale (9) | 4–0 | Welling Town (9) | |
| 130 | Tunbridge Wells (9) | 4–1 | Canterbury City (9) | |
| 131 | Epsom & Ewell (10) | 4–0 | Mile Oak (10) | 56 |
| 132 | Holmesdale (9) | 4–0 | AFC Croydon Athletic (10) | |
| 133 | Alfold (9) | 2–2 (3–4 p) | Redhill (9) | 85 |
| 135 | Fisher (9) | Little Common (9) | ||
| Fisher awarded a walkover due to Little Common players and staff testing positive for COVID-19, forcing them to forfeit.[6] | ||||
| 136 | Rochester United (10) | 1–1 (7–6 p) | Chessington & Hook United (10) | |
| 137 | Snodland Town (10) | 4–1 | Sutton Athletic (10) | |
| 138 | Abbey Rangers (9) | 4–2 | Montpelier Villa (10) | |
| 140 | Hassocks (9) | 1–2 | Beckenham Town (9) | 90 |
| 141 | Lordswood (9) | 1–1 (4–2 p) | Seaford Town (10) | |
| 142 | Croydon (10) | 1–4 | Horley Town (9) | |
| 143 | Erith Town (9) | 2–3 | Sheppey United (9) | |
| 144 | Saltdean United (9) | 1–3 | Bridon Ropes (10) | 76 |
| 145 | Colliers Wood United (9) | 1–0 | Punjab United (9) | |
| 146 | Tower Hamlets (9) | 1–3 | Crawley Down Gatwick (9) | |
| 147 | Hailsham Town (10) | 1–2 | Staplehurst Monarchs (10) | 97 |
| 148 | Greenways (10) | 2–3 | Forest Hill Park (10) | |
| 149 | Athletic Newham (9) | 2–2 (7–6 p) | Bexhill United (9) | 36 |
| 150 | Loxwood (9) | 0–5 | Erith & Belvedere (9) | 58 |
| 151 | Worthing United (10) | 1–5 | Stansfeld (10) | 65 |
| 152 | Midhurst & Easebourne (10) | 0–1 | Alresford Town (9) | 87 |
| 153 | Ringwood Town (10) | 1–2 | Downton (10) | 82 |
| 154 | Moneyfields (9) | 2–0 | AFC Portchester (9) | |
| 155 | Laverstock & Ford (10) | 4–0 | Fawley (10) | 102 |
| 156 | Whitchurch United (10) | 2–2 (3–5 p) | Ash United (10) | 96 |
| 157 | Godalming Town (10) | 2–2 (4–5 p) | Badshot Lea (9) | 124 |
| 158 | Sherborne Town (10) | 3–6 | Bemerton Heath (10) | |
| 159 | Horndean (9) | 1–1 (1–4 p) | Brockenhurst (9) | 84 |
| 160 | Bournemouth (9) | 5–3 | East Cowes Victoria Athletic (10) | 76 |
| 161 | Alton (9) | 2–2 (3–5 p) | Pagham (9) | 153 |
| 162 | Andover Town (10) | 1–4 | Andover New Street (10) | 279 |
| 163 | AFC Stoneham (9) | 2–3 | Blackfield & Langley (9) | 53 |
| 164 | Arundel (10) | 0–5 | Shaftesbury (9) | 60 |
| 165 | Bradford Town (9) | 2–0 | Odd Down (10) | 107 |
| 166 | Corsham Town (9) | 1–1 (2–4 p) | Hamworthy United (9) | 99 |
| 167 | Farnham Town (9) | 1–1 (6–7 p) | Bashley (9) | |
| 168 | Wendron United (10) | 2–1 | Bishop Sutton (10) | 105 |
| 169 | St Blazey (10) | 2–2 (5–6 p) | Dobwalls (10) | |
| 170 | Wadebridge Town (10) | 1–4 | Newquay (10) | 103 |
| 171 | Elmore (10) | 1–5 | Helston Athletic (9) | |
| 172 | Shepton Mallet (9) | 0–1 | Mousehole (9) | 208 |
| 173 | Launceston (10) | 1–2 | Newton Abbot Spurs (10) | |
| 174 | Sidmouth Town (10) | 2–10 | Welton Rovers (10) | |
| 175 | Bovey Tracey (10) | 4–6 | Street (9) | |
| 176 | Porthleven (10) | Liskeard Athletic (10) | ||
| Liskeard Athletic awarded a walkover due to Porthleven resigning from the South West Peninsula League.[7] | ||||
| 177 | Bishops Lydeard (10) | 2–2 (2–4 p) | Wellington AFC (9) | 85 |
| 178 | Camelford (10) | 3–2 | Cheddar (10) | 65 |
| 179 | Saltash United (9) | 2–2 (5–4 p) | Bodmin Town (10) | 153 |
| Saltash United removed from competition for fielding an ineligible player.[8] | ||||
| 180 | Axminster Town (10) | 0–1 | Brixham (10) | |
| 181 | Torpoint Athletic (10) | 6–1 | Stoke Gabriel (10) | |
| 182 | Ivybridge Town (10) | 1–2 | Wells City (10) | |
| Sunday, 26 September 2021 | ||||
| 16 | Albion Sports (9) | 1–8 | Newcastle Benfield (9) | 123 |
| 77 | Newbury Forest (10) | 1–7 | Buckhurst Hill (10) | |
| 88 | Benfleet (10) | 6–1 | Holland (10) | 62 |
| 100 | Hilltop (10) | 3–1 | Broadfields United (9) | |
| 126 | Sandhurst Town (10) | 1–3 | Longlevens (9) | |
| 139 | Jersey Bulls (9) | 5–0 | Crowborough Athletic (9) | 778 |
The draw was made on 27 September 2021.[9]
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| 55 | Risborough Rangers (9) | 3–1 | Long Melford (9) | 115 |
| 57 | Holmer Green (9) | 1–3 | Glebe (9) | 59 |
| 58 | Newmarket Town (9) | 2–1 | Redbridge (9) | 151 |
| 59 | London Lions (10) | 4–2 | Thetford Town (9) | 79 |
| 60 | North Greenford United (9) | 3–2 | Ash United (10) | 60 |
| 61 | Fisher (9) | 1–2 | Badshot Lea (9) | 162 |
| 62 | Rayners Lane (10) | 2–3 | Sheerwater (9) | 64 |
| 63 | Hilltop (10) | 2–3 | Tunbridge Wells (9) | |
| 66 | Abbey Rangers (9) | 2–2 (4–2 p) | Horley Town (9) | 62 |
| 67 | Littlehampton Town (9) | 3–2 | Moneyfields (9) | 202 |
| 68 | British Airways (10) | 4–0 | Epsom & Ewell (10) | |
| 69 | Clapton (9) | 0–2 | Beckenham Town (9) | |
| 70 | Pagham (9) | 1–1 (4–2 p) | Snodland Town (10) | 104 |
| 71 | Wallingford Town (10) | 2–2 (6–5 p) | Ascot United (9) | |
| 72 | Stansfeld (10) | 3–1 | Staplehurst Monarchs (10) | 81 |
| 73 | Blackfield & Langley (9) | 4–2 | Wokingham & Emmbrook (9) | 83 |
| 74 | Sheppey United (9) | 4–0 | Forest Hill Park (10) | 289 |
| 75 | Chatham Town (9) | 6–0 | Alresford Town (9) | 388 |
| 76 | Holmesdale (9) | 1–1 (5–6 p) | Athletic Newham (9) | 49 |
| 77 | Milton United (10) | 2–1 | Bridon Ropes (10) | 79 |
| 78 | Harefield United (9) | 3–0 | Kent Football United (10) | 70 |
| 79 | Guildford City (9) | 4–0 | Shoreham (10) | 74 |
| 80 | Deal Town (9) | 4–0 | Kennington (9) | 423 |
| 81 | Frimley Green (9) | 2–1 | Rochester United (10) | 93 |
| 82 | Berks County (10) | 2–1 | Burnham (9) | |
| 83 | Crawley Down Gatwick (9) | 3–2 | Lordswood (9) | 103 |
| 84 | Egham Town (9) | 4–1 | Colliers Wood United (9) | 84 |
| 85 | Raynes Park Vale (9) | 2–0 | Redhill (9) | 107 |
| 86 | Dobwalls (10) | 0–3 | Bashley (9) | 79 |
| 87 | Royal Wootton Bassett Town (9) | 4–0 | Downton (10) | 148 |
| 88 | Wendron United (10) | 4–2 | Bournemouth (9) | 118 |
| 89 | Buckland Athletic (9) | 3–0 | Camelford (10) | 125 |
| 90 | Newton Abbot Spurs (10) | 1–2 | Brixham (10) | |
| 91 | Tuffley Rovers (9) | 1–4 | Street (9) | 70 |
| 92 | Cribbs (9) | 1–2 | Andover New Street (10) | 105 |
| 93 | Liskeard Athletic (10) | 4–2 | Laverstock & Ford (10) | |
| 94 | Bitton (9) | 2–4 | New Milton Town (10) | 53 |
| 95 | Oldland Abbotonians (10) | 2–2 (5–3 p) | Helston Athletic (9) | 55 |
| 96 | Brimscombe & Thrupp (9) | 2–1 | Welton Rovers (10) | 84 |
| 97 | Mousehole (9) | 4–0 | Wells City (10) | 118 |
| 98 | Brockenhurst (9) | 6–0 | Bodmin Town (10) | 204 |
| 99 | Longlevens (9) | 0–3 | Shaftesbury (9) | 86 |
| 100 | Newquay (10) | 2–3 | Keynsham Town (9) | 200 |
| 101 | Millbrook AFC (9) | 1–2 | Wellington AFC (9) | |
| 102 | Ashton & Backwell United (9) | 0–0 (4–5 p) | Bemerton Heath (10) | 119 |
| 103 | Falmouth Town (10) | 2–1 | Bradford Town (9) | 570 |
| 104 | Torpoint Athletic (10) | 4–1 | Chipping Sodbury Town (9) | 100 |
| 105 | Cadbury Heath (9) | 1–1 (5–6 p) | Hamworthy United (9) | 65 |
| 12 | Billingham Synthonia (10) | 4–2 | FC Isle of Man (10) | 150 |
| Sunday, 24 October 2021 | ||||
| 36 | Coventry United (9) | 2–1 | Birstall United (10) | 271 |
| 10 | AFC Liverpool (9) | 2–1 | Newton Aycliffe (9) | 127 |
| 30 | Belper United (10) | 1–2 | Rugby Town (9) | 177 |
| 56 | Baldock Town (9) | 5–1 | Hillingdon Borough (10) | 104 |
The draw was made on 25 October 2021 featuring the 105 winners from the previous round with an additional 23 teams joining.[10]
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| Friday, 19 November 2021 | ||||
| 59 | Brixham (10) | 1–5 | Tavistock (9) | |
| Tavistock removed from competition for fielding an ineligible player.[11] | ||||
| Saturday, 20 November 2021 | ||||
| 1 | Pilkington (10) | 3–1 | Burscough (9) | 118 |
| 2 | AFC Liverpool (9) | 2–0 | Redcar Town (10) | 147 |
| 3 | Eccleshill United (9) | 2–3 | Barton Town (9) | 89 |
| 4 | Newcastle Benfield (9) | 2–0 | Emley AFC (9) | 182 |
| 5 | Carlisle City (10) | 0–1 | Abbey Hey (10) | 220 |
| 6 | North Shields (9) | 2–2 (6–5 p) | North Ferriby (10) | 410 |
| 8 | Holker Old Boys (10) | 0–3 | Wythenshawe Town (9) | 81 |
| 9 | Billingham Synthonia (10) | 2–1 | West Auckland Town (9) | 130 |
| 10 | Thornaby (9) | 1–1 (3–4 p) | Consett (9) | 228 |
| 11 | Prestwich Heys (9) | 3–1 | Winterton Rangers (9) | 206 |
| 12 | Sandbach United (10) | 1–0 | Hanley Town (9) | 160 |
| 13 | Lichfield City (9) | 3–0 | Highgate United (9) | 206 |
| 14 | Stourport Swifts (9) | 3–1 | Kimberley MW (10) | 142 |
| 15 | Atherstone Town (10) | 3–1 | Long Eaton United (9) | 424 |
| 16 | Rugby Town (9) | 1–0 | Hinckley LR (9) | 194 |
| 17 | Loughborough Students (9) | 2–0 | Gresley Rovers (9) | 464 |
| 18 | Racing Club Warwick (9) | 1–3 | Coventry Sphinx (9) | 306 |
| 19 | Aylestone Park (10) | 1–5 | Anstey Nomads (9) | 161 |
| 20 | Boldmere St. Michaels (9) | 1–1 (2–4 p) | Congleton Town (9) | 116 |
| 21 | Whitchurch Alport (9) | 1–1 (5–3 p) | Malvern Town (9) | 239 |
| 22 | Coventry United (9) | 1–1 (5–4 p) | Westfields (9) | 115 |
| 23 | Harborough Town (9) | 2–0 | Wellingborough Town (9) | 246 |
| 24 | Whittlesey Athletic (10) | 0–0 (7–6 p) | Worcester City (9) | 314 |
| 25 | Walsall Wood (9) | 2–0 | Deeping Rangers (9) | 30 |
| 26 | Mulbarton Wanderers (9) | 1–2 | London Lions (10) | 76 |
| 27 | Shefford Town & Campton (10) | 1–1 (5–4 p) | Risborough Rangers (9) | 292 |
| 28 | Cockfosters (9) | 0–4 | Tring Athletic (9) | 186 |
| 29 | Saffron Walden Town (9) | 5–1 | Cornard United (10) | 284 |
| 30 | Fakenham Town (9) | 1–1 (4–2 p) | Stansted (9) | 148 |
| 32 | New Salamis (9) | 2–0 | Ipswich Wanderers (10) | 35 |
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| 33 | Norwich CBS (10) | 0–3 | Lakenheath (9) | ||
| 34 | Newport Pagnell Town (9) | 1–1 (2–1 p) | Leighton Town (9) | 526 | |
| 35 | Gorleston (9) | 2–3 | Buckhurst Hill (10) | 165 | |
| 36 | Wroxham (9) | 1–1 (6–5 p) | Newmarket Town (9) | 145 | |
| 37 | Glebe (9) | 1–1 (5–3 p) | Hanworth Villa (9) | 65 | |
| 38 | Deal Town (9) | 1–2 | Littlehampton Town (9) | 407 | |
| 39 | Crawley Down Gatwick (9) | 3–0 | British Airways (10) | 90 | |
| 40 | Flackwell Heath (9) | 0–1 | Guildford City (9) | 167 | |
| 41 | Raynes Park Vale (9) | 6–2 | Blackfield & Langley (9) | 102 | |
| 42 | Fareham Town (9) | 3–5 | Abbey Rangers (9) | 256 | |
| 43 | Milton United (10) | 2–3 | Beckenham Town (9) | 87 | |
| 44 | Cobham (9) | 0–3 | Egham Town (9) | ||
| 45 | Frimley Green (9) | 5–1 | United Services Portsmouth (9) | 65 | |
| 47 | Tunbridge Wells (9) | 1–0 | Walton & Hersham (9) | 329 | |
| 48 | Southall (9) | 2–2 (3–1 p) | Chatham Town (9) | 108 | |
| 49 | Wallingford Town (10) | 1–0 | North Greenford United (9) | ||
| 50 | Harefield United (9) | 2–3 | Berks County (10) | 150 | |
| 51 | Sheerwater (9) | 2–3 | Sheppey United (9) | ||
| 52 | Athletic Newham (9) | 5–3 | Pagham (9) | ||
| 53 | Wellington AFC (9) | 5–2 | Christchurch (9) | 51 | |
| 54 | Buckland Athletic (9) | 3–1 | Falmouth Town (10) | 302 | |
| 55 | Wendron United (10) | 3–6 | New Milton Town (10) | ||
| 56 | Andover New Street (10) | 1–2 | Hamworthy United (9) | 187 | |
| 57 | Liskeard Athletic (10) | 2–3 | Keynsham Town (9) | 148 | |
| 58 | Royal Wootton Bassett Town (9) | 2–0 | Torpoint Athletic (10) | 293 | |
| 60 | Bemerton Heath (10) | 1–4 | Clevedon Town (9) | 103 | |
| 61 | Bashley (9) | 2–2 (6–5 p) | Shaftesbury (9) | 230 | |
| 62 | Street (9) | 1–1 (5–4 p) | Oldland Abbotonians (10) | ||
| 63 | Bridgwater United (9) | 1–0 | Mousehole (9) | 327 | |
| 64 | Brockenhurst (9) | 4–1 | Brimscombe & Thrupp (9) | 224 | |
| Sunday, 21 November 2021 | |||||
| 7 | Bury AFC (10) | 3–1 | Birtley Town (10) | 1,019 | |
| 31 | Baldock Town (9) | 2–2 (4–5 p) | Hadley (9) | 105 | |
| 46 | Stansfeld (10) | 2–1 | Badshot Lea (9) | 177 | |
The draw was made on 22 November 2021.[12]
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| Saturday, 11 December 2021 | |||||
| 2 | Abbey Hey (10) | 4–1 | Bury AFC (10) | 650 | |
| 3 | Newcastle Benfield (9) | 0–4 | Consett (9) | 351 | |
| 4 | Barton Town (9) | 2–3 | North Shields (9) | 520 | |
| 5 | Wythenshawe Town (9) | 3–0 | Billingham Synthonia (10) | 182 | |
| 6 | Stourport Swifts (9) | 2–2 (4–5 p) | Rugby Town (9) | 123 | |
| 7 | Loughborough Students (9) | 4–0 | Sandbach United (10) | 301 | |
| 8 | Atherstone Town (10) | 1–3 | Whitchurch Alport (9) | 395 | |
| 9 | Coventry Sphinx (9) | 1–0 | Coventry United (9) | 185 | |
| 10 | Prestwich Heys (9) | P–P | Harborough Town (9) | ||
| 11 | Highgate United (9) | 0–4 | Congleton Town (9) | 81 | |
| 12 | Walsall Wood (9) | P–P | Anstey Nomads (9) | ||
| 13 | Whittlesey Athletic (10) | 0–6 | Newport Pagnell Town (9) | 359 | |
| 14 | Tring Athletic (9) | 0–1 | Saffron Walden Town (9) | 114 | |
| 15 | London Lions (10) | 2–0 | New Salamis (9) | 104 | |
| 16 | Buckhurst Hill (10) | 2–3 | Wroxham (9) | ||
| 17 | Lakenheath (9) | 3–2 | Shefford Town & Campton (10) | 131 | |
| 18 | Fakenham Town (9) | 3–1 | Hadley (9) | 166 | |
| 19 | Tunbridge Wells (9) | 4–2 | Wallingford Town (10) | 336 | |
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| 20 | Glebe (9) | 0–0 (4–3 p) | Beckenham Town (9) | 175 | |
| 21 | Abbey Rangers (9) | 1–1 (2–4 p) | Athletic Newham (9) | ||
| 24 | Crawley Down Gatwick (9) | 0–4 | Raynes Park Vale (9) | 104 | |
| 25 | Littlehampton Town (9) | 1–0 | Sheppey United (9) | 275 | |
| 26 | Guildford City (9) | 0–0 (3–4 p) | Southall (9) | 130 | |
| 27 | New Milton Town (10) | 0–0 (4–3 p) | Keynsham Town (9) | ||
| 28 | Bridgwater United (9) | 2–1 | Bashley (9) | ||
| 29 | Street (9) | 1–1 (2–3 p) | Brockenhurst (9) | 160 | |
| 30 | Buckland Athletic (9) | 2–0 | Wellington AFC (9) | 152 | |
| 31 | Royal Wootton Bassett Town (9) | 1–3 | Hamworthy United (9) | 201 | |
| 32 | Brixham (10) | 0–6 | Clevedon Town (9) | ||
| Sunday, 12 December 2021 | |||||
| 1 | AFC Liverpool (9) | 1–0 | Pilkington (10) | 142 | |
| 23 | Berks County (10) | 1–2 | Egham Town (9) | ||
| 22 | Stansfeld (10) | 3–1 | Frimley Green (9) | 232 | |
| Saturday, 18 December 2021 | |||||
| 10 | Prestwich Heys (9) | 1–7 | Harborough Town (9) | 222 | |
| 12 | Walsall Wood (9) | 1–1 (4–2 p) | Anstey Nomads (9) | 70 | |
| Tie awarded to Anstey Nomads. | |||||
The draw was made on 13 December 2021.[13]
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| Saturday, 15 January 2022 | ||||
| 1 | Consett (9) | 1–2 | Wythenshawe Town (9) | 585 |
| 2 | Abbey Hey (10) | 2–2 (6–5 p) | AFC Liverpool (9) | 270 |
| 3 | Harborough Town (9) | 1–1 (3–5 p) | North Shields (9) | 1,014 |
| 4 | Whitchurch Alport (9) | 2–1 | Congleton Town (9) | 457 |
| 6 | Rugby Town (9) | 5–1 | Lakenheath (9) | 434 |
| 7 | Saffron Walden Town (9) | 1–1 (5–6 p) | Loughborough Students (9) | 760 |
| 8 | Coventry Sphinx (9) | 6–0 | London Lions (10) | 115 |
| 9 | Newport Pagnell Town (9) | 3–1 | Fakenham Town (9) | 616 |
| Tie | Home team (tier) | Score | Away team (tier) | |
|---|---|---|---|---|
| 10 | Brockenhurst (9) | 2–0 | New Milton Town (10) | 857 |
| 11 | Bridgwater United (9) | 2–2 (3–5 p) | Tunbridge Wells (9) | 336 |
| 12 | Hamworthy United (9) | 3–2 | Glebe (9) | 214 |
| 13 | Athletic Newham (9) | 5–0 | Littlehampton Town (9) | 152 |
| Athletic Newham removed from competition for fielding an ineligible player.[14] | ||||
| 14 | Buckland Athletic (9) | 2–1 | Egham Town (9) | 312 |
| 15 | Southall (9) | 1–1 (5–4 p) | Clevedon Town (9) | |
| 16 | Raynes Park Vale (9) | 1–2 | Stansfeld (10) | |
| Saturday, 22 January 2022 | ||||
| 5 | Wroxham (9) | 2–5 | Anstey Nomads (9) | |
The draw was made on 17 January 2022.[15]
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| Saturday, 12 February 2022 | |||||
| 1 | Coventry Sphinx (9) | 3–3 | Whitchurch Alport (9) | 338 | |
| 2 | North Shields (9) | 2–0 | Rugby Town (9) | 1,039 | |
| 3 | Loughborough Students (9) | 3–0 | Abbey Hey (10) | 873 | |
| 4 | Anstey Nomads (9) | 1–1 | Wythenshawe Town (9) | 430 | |
| 5 | Southall (9) | 0–0 | Stansfeld (10) | 245 | |
| 6 | Hamworthy United (9) | 3–1 | Tunbridge Wells (9) | 661 | |
| 7 | Littlehampton Town (9) | 3–3 | Brockenhurst (9) | 1,276 | |
| 8 | Newport Pagnell Town (9) | 1–1 | Buckland Athletic (9) | 1,186 | |
The draw for the quarter-finals was made on 14 February 2022.[16]
| Tie | Home team (tier) | Score | Away team (tier) | ||
|---|---|---|---|---|---|
| Saturday, 12 March 2022 | |||||
| 1 | Whitchurch Alport (9) | 1–2 | Newport Pagnell Town (9) | 1,200 | |
| 2 | Loughborough Students (9) | 2–0 | Wythenshawe Town (9) | 1,081 | |
| 3 | Littlehampton Town (9) | 1–0 | North Shields (9) | 2,245 | |
| 4 | Hamworthy United (9) | 1–1 (7–6 p) | Southall (9) | 783[17] | |
The draw for the semi-finals was made on 14 March 2022.[18]
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See main article: 2022 FA Vase final.