| Club: | Cosenza Calcio |
| Chairman: | Eugenio Guarascio |
| Manager: | Roberto Occhiuzzi |
| Stadium: | Stadio San Vito-Gigi Marulla |
| League: | Serie B |
| League Result: | 16th (play-off winners) |
| Cup1: | Coppa Italia |
| Cup1 Result: | First round |
| League Topscorer: | Gabriele Gori (5) |
| Season Topscorer: | Gabriele Gori (5) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was Cosenza Calcio's fourth consecutive season in second division of the Italian football league, the Serie B, and the 108th as a football club.
| scope=col | Player | Transferred from | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 17 | Empoli | Loan | [1] | |||||||
| 95 | Paris FC | Loan | [2] |
See main article: 2021–22 Serie B.
The league fixtures were announced on 24 July 2021.[3]
See main article: 2021–22 Coppa Italia.