| Club: | Cercle Brugge |
| Season: | 2021–22 |
| Owner: | Dmitry Rybolovlev |
| Mgrtitle: | Manager |
| Manager: | Yves Vanderhaeghe (until 28 November) Dominik Thalhammer (from 28 November) |
| Stadium: | Jan Breydel Stadium |
| League: | First Division A |
| League Result: | 10th |
| Cup1: | Belgian Cup |
| Cup1 Result: | Seventh round |
| League Topscorer: | Rabbi Matondo (9) |
| Season Topscorer: | Rabbi Matondo (9) |
| Pattern La1: | _cercle2122h |
| Pattern B1: | _cercle2122h |
| Pattern Ra1: | _cercle2122h |
| Pattern Sh1: | _cercle2021h |
| Leftarm1: | 000000 |
| Body1: | 006b20 |
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| Socks1: | 006b20 |
| Pattern La2: | _cercle2122a |
| Pattern B2: | _cercle2122a |
| Pattern Ra2: | _cercle2122a |
| Pattern Sh2: | _cercle2021a |
| Leftarm2: | FFFFFF |
| Body2: | FFFFFF |
| Rightarm2: | FFFFFF |
| Shorts2: | FFFFFF |
| Socks2: | FFFFFF |
| Pattern La3: | _cercle2122t |
| Pattern B3: | _cercle2122t |
| Pattern Ra3: | _cercle2122t |
| Pattern Sh3: | _cercle2021h |
| Leftarm3: | 000000 |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 123rd season in the existence of Cercle Brugge K.S.V. and the club's 27th consecutive season in the top flight of Belgian football. In addition to the domestic league, Cercle Brugge K.S.V. will participate in this season's edition of the Belgian Cup.
See main article: 2021–22 Belgian First Division A.
The league fixtures were announced on 8 June 2021.[2]
See main article: 2021–22 Belgian Cup.