| Club: | CA Osasuna |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: | Luis Sabalza |
| Mgrtitle: | Head coach |
| Manager: | Jagoba Arrasate |
| Stadium: | El Sadar |
| League: | La Liga |
| League Result: | 10th |
| Cup1: | Copa del Rey |
| Cup1 Result: | Round of 32 |
| League Topscorer: | Ante Budimir (8) |
| Season Topscorer: | Ante Budimir (9) |
| Pattern Name1: | Home |
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| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 91st season in the existence of CA Osasuna and the club's third consecutive season in the top flight of Spanish football. In addition to the domestic league, Osasuna participated in this season's edition of the Copa del Rey.
See main article: CA Osasuna B.
| Date | Player | From | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [2] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [3] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [4] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [5] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [6] | ||
| 1 July 2021 | Buyout clause | €8M | [7] | ||
| 1 July 2021 | Transfer | Free | [8] | ||
| Date | Player | To | Type | Fee | Ref |
|---|---|---|---|---|---|
| 30 June 2021 | align=center colspan=2 | Loan return | [9] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [10] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [11] | ||
| 30 June 2021 | align=center colspan=2 | Loan return | [12] | ||
| 1 July 2021 | Transfer | Free | [13] | ||
See main article: 2021–22 La Liga.
The league fixtures were announced on 30 June 2021.[14] [15]
See main article: 2021–22 Copa del Rey.
Last updated 22 May 2022|-! colspan=14 style=background:#dcdcdc; text-align:center|Goalkeepers|-! colspan=14 style=background:#dcdcdc; text-align:center|Defenders|-! colspan=14 style=background:#dcdcdc; text-align:center|Midfielders|-! colspan=14 style=background:#dcdcdc; text-align:center|Forwards|-! colspan=14 style=background:#dcdcdc; text-align:center| Players who have made an appearance or had a squad number this season but have been loaned out or transferred|}
| Rank | Player | La Liga | Copa del Rey | Total | |
|---|---|---|---|---|---|
| 1 | Ante Budimir | 7 | 1 | 8 | |
| 2 |  Ezequiel Ávila | 6 | 1 | 7 | |
| 3 |  Kike García | 5 | 1 | 6 | |
| 4 | David García | 4 | 0 | 4 | |
| 5 | Roberto Torres | 2 | 1 | 3 | |
| 6 | Jon Moncayola | 2 | 0 | 2 | |
| 7 | José Ángel | 1 | 0 | 1 | |
| Iván Barbero | 0 | 1 | 1 | ||
| Kike Barja | 1 | 0 | 1 | ||
| Rubén García | 1 | 0 | 1 | ||
| Javi Martínez | 1 | 0 | 1 | ||
| Javier Ontiveros | 0 | 1 | 1 | ||
| Iñigo Pérez | 1 | 0 | 1 | ||
| Manu Sánchez | 1 | 0 | 1 | ||
| Lucas Torró | 1 | 0 | 1 | ||
| align=center colspan=2 | Own goals | 1 | 0 | 1 | |
| Total | 34 | 6 | 40 | ||