| Club: | Brøndby |
| Season: | 2021–22 |
| Manager: | Niels Frederiksen |
| Mgrtitle: | Head coach |
| Chairman: | Jan Bech Andersen |
| Chrtitle: | Chairman |
| Stadium: | Brøndby Stadium |
| Stdtitle: | Stadium |
| League: | Danish Superliga |
| League Result: | 3rd |
| Cup1: | Danish Cup |
| Cup1 Result: | Quarter-finals |
| Cup2: | UEFA Champions League |
| Cup2 Result: | Play-off round |
| Cup3: | UEFA Europa League |
| Cup3 Result: | Group stage |
| League Topscorer: | Mikael Uhre (11 goals) |
| Season Topscorer: | Mikael Uhre (14 goals) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 Brøndby IF season was Brøndby IF's 41st consecutive season in top-division of the Danish football league, the 32nd consecutive in Danish Superliga, and the 56th as a football club. Besides the Superliga, the club also competed in the Danish Cup and this season's editions of the UEFA Champions League and UEFA Europa League. It is the third season with head coach Niels Frederiksen, after he replaced caretaker manager Martin Retov during the 2019–20 campaign.
Brøndby entered this season as reigning Danish Superliga champions, having won the league title for the first time in 16 years in 2021.[1]
| scope=col | Player | Transferred from | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 16 | Lyngby | Free | [3] [4] | |||||||
| 21 | IFK Göteborg | Undisclosed | [5] | |||||||
| 3 | Viking | Undisclosed | [6] [7] | |||||||
| 24 | DAC 1904 | Loan | [8] |
| scope=col | Player | Transferred to | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 16 | Unattached | End of contract | [9] | |||||||
| 21 | Zulte Waregem | Undisclosed | [10] [11] | |||||||
| 3 | Werder Bremen | Free | [12] | |||||||
| 1 | 1. FC Köln | Free | [13] | |||||||
| 18 | Eintracht Frankfurt | €7.0 million | [14] | |||||||
| 6 | Pisa | Undisclosed | [15] | |||||||
| 24 | Randers | Undisclosed | [16] | |||||||
| 7 | Lyngby | Undisclosed | [17] [18] |
See main article: 2021–22 Danish Superliga.
See main article: 2021–22 Danish Cup.
See main article: 2021–22 UEFA Champions League.
See main article: 2021–22 UEFA Europa League.
The draw for the group stage was held on 27 August 2021.[19]
| Rank | Player | Danish Superliga | Danish Cup | Champions League | Europa League | Total | |
|---|---|---|---|---|---|---|---|
| 1 | Mikael Uhre | 11 | 1 | 1 | 1 | 14 | |
| 2 |  Christian Cappis | 3 | 2 | 0 | 0 | 5 | |
| 3 |  Andrija Pavlović | 0 | 3 | 0 | 0 | 3 | |
| 4 | Marko Divković | 0 | 2 | 0 | 0 | 2 | |
 Oskar Fallenius | 0 | 2 | 0 | 0 | 2 | ||
| Morten Frendrup | 2 | 0 | 0 | 0 | 2 | ||
| Andreas Maxsø | 1 | 0 | 1 | 0 | 2 | ||
| Jagvir Singh | 0 | 2 | 0 | 0 | 2 | ||
| 9 |  Tobias Børkeeiet | 1 | 0 | 0 | 0 | 1 | |
| Andreas Bruus | 1 | 0 | 0 | 0 | 1 | ||
| Simon Hedlund | 1 | 0 | 0 | 0 | 1 | ||
| Michael Lumb | 0 | 1 | 0 | 0 | 1 | ||
| Kevin Mensah | 1 | 0 | 0 | 0 | 1 | ||
| Josip Radošević | 1 | 0 | 0 | 0 | 1 | ||
| Sigurd Rosted | 1 | 0 | 0 | 0 | 1 | ||
 Anis Ben Slimane | 1 | 0 | 0 | 0 | 1 | ||
| align=center colspan=2 | Own goals | 1 | 0 | 0 | 1 | 2 | |
| Total | 25 | 13 | 2 | 2 | 42 | ||