| Club: | İstanbul Başakşehir |
| Season: | 2021–22 |
| Chrtitle: | President |
| Chairman: | Göksel Gümüşdağ |
| Mgrtitle: | Head coach |
| Manager: | Aykut Kocaman (until 2 October) Emre Belözoğlu (from 3 October) |
| Stadium: | Başakşehir Fatih Terim Stadium |
| League: | Süper Lig |
| League Result: | 4th |
| Cup1: | Turkish Cup |
| Cup1 Result: | Fourth round |
| League Topscorer: | Stefano Okaka (12) |
| Season Topscorer: | Stefano Okaka (12) |
| Highest Attendance: | 2,609 (vs. Beşiktaş, 15 October 2021, Süper Lig) |
| Lowest Attendance: | 221 (vs. Kayserispor, 28 August 2021, Süper Lig) |
| Average Attendance: | 779 |
| Largest Win: | 3–0(vs. Çaykur Rizespor (H), 26 September 2021, Süper Lig vs. Hatayspor (A), 5 December 2021, Süper Lig) |
| Largest Loss: | 1–3(vs. Fatih Karagümrük (A), 1 October 2021, Süper Lig) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 season was the 32nd season in the existence of İstanbul Başakşehir and the club's eighth consecutive season in the top flight of Turkish football. In addition to the domestic league, İstanbul Başakşehir participated in this season's edition of the Turkish Cup.
İstanbul Başakşehir's 2021–22 home and away kits, manufactured by Bilcee, released on 11 August 2021 and were up for sale on the same day. The third jersey was introduced separately on 3 September 2021, in a special screening.
See main article: 2021–22 Süper Lig.
See main article: 2021–22 Turkish Cup.
| width=15 | width=15 | width=15 | width=15 | width=145 | Name | width=100 | Süper Lig | width=100 | Turkish Cup | width=100 | Total | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 77 | FW |  | Stefano Okaka | 10 | 0 | 10 | ||||||||
| 2 | 8 | MF |  | Danijel Aleksić | 6 | 0 | 6 | ||||||||
| 3 | 23 | MF |  | Deniz Türüç | 5 | 0 | 5 | ||||||||
| 27 | FW |  | Trézéguet | 5 | 0 | 5 | |||||||||
| 5 | 7 | MF |  | Edin Višća | 4 | 0 | 4 | ||||||||
| 22 | FW |  | Fredrik Gulbrandsen | 4 | 0 | 4 | |||||||||
| 7 | 10 | MF | | Berkay Özcan | 3 | 0 | 3 | ||||||||
| 21 | MF | | Mahmut Tekdemir | 3 | 0 | 3 | |||||||||
| 9 | 80 | DF |  | Júnior Caiçara | 2 | 0 | 2 | ||||||||
| 10 | 11 | MF |  | Nacer Chadli | 1 | 0 | 1 | ||||||||
| 17 | FW | | Ahmed Kutucu | 0 | 1 | 1 | |||||||||
| 20 | MF | Pizzi | 1 | 0 | 1 | ||||||||||
| 28 | MF | | Tolga Ciğerci | 1 | 0 | 1 | |||||||||
| 55 | MF |  | Youssouf Ndayishimiye | 1 | 0 | 1 | |||||||||
| Own goals | 2 | 0 | 2 | ||||||||||||
| Totals | 48 | 1 | 49 | ||||||||||||