| Champ: |  Jannik Sinner |
| Runner: |  Vasek Pospisil |
| Score: | 6–4, 3–6, 7–6(7–3) |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| Type: | singles doubles |
| Before Name: | Sofia Open – Singles |
| After Name: | Sofia Open – Singles |
| Main Name: | ATP Sofia Open |
See main article: article and 2020 Sofia Open.
Jannik Sinner defeated Vasek Pospisil in the final, 6–4, 3–6, 7–6(7–3) to win the singles tennis title at the 2020 Sofia Open. It was his first ATP Tour title.
Daniil Medvedev was the reigning champion,[1] but chose not to defend his title.
The top four seeds received a bye into the second round.