| Champ: |  Thiago Seyboth Wild |
| Runner: |  Casper Ruud |
| Score: | 7–5, 4–6, 6–3 |
| Draw: | 28 |
| Seeds: | 8 |
| Type: | singles doubles |
| Before Name: | Royal Guard Open |
| Before Year: | 2014 |
See main article: 2020 Chile Open.
Fabio Fognini was the champion in 2014, when the event was last held,[1] but chose to compete in Dubai instead.
Thiago Seyboth Wild won his first ATP Tour title, defeating Casper Ruud in the final, 7–5, 4–6, 6–3. Seyboth Wild also becomes the first player born in 2000 to win an ATP Tour title.
The top four seeds received a bye into the second round.