| Champ: |  Shingo Kunieda |
| Runner: |  Gordon Reid |
| Score: | 6–4, 6–4 |
| Before Name: | Australian Open – Wheelchair men's singles |
| After Name: | Australian Open – Wheelchair men's singles |
See main article: 2020 Australian Open.
Shingo Kunieda defeated Gordon Reid in the final, 6–4, 6–4 to win the men's singles wheelchair tennis title at the 2020 Australian Open. It was his tenth Australian Open singles title and 23rd major singles title overall.
Gustavo Fernández was the defending champion, but was defeated by Reid in the quarterfinals.