| Champ: |  Patricia Maria Țig |
| Runner: |  Eugenie Bouchard |
| Score: | 2–6, 6–1, 7–6(7–4) |
| Draw: | 30 |
| Seeds: | 8 |
| Type: | singles doubles |
| Before Name: | İstanbul Cup – Singles |
| After Name: | İstanbul Cup – Singles |
See main article: 2020 İstanbul Cup.
Petra Martić was the defending champion, but she chose not to participate as she was still competing at the 2020 US Open.[1]
Patricia Maria Țig won her maiden WTA tour-level singles title, defeating Eugenie Bouchard in the final, 2–6, 6–1, 7–6(7–4).[2]