| Mode: | Women's basketball |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | Oklahoma State Cowgirls |
| Conference: | Big 12 Conference |
| Short Conf: | Big 12 |
| Record: | 19–9 |
| Conf Record: | 13–5 |
| Head Coach: | Jim Littell |
| Hc Year: | 10th |
| Asst Coach1: | Bill Annan |
| Asst Coach2: | Ashley Davis |
| Asst Coach3: | Jerise Freeman |
| Stadium: | Gallagher-Iba Arena |
| Bowl: | NCAA tournament |
| Bowl Result: | second round |
The 2020–21 Oklahoma State Cowgirls basketball team represented Oklahoma State University in the 2020–21 NCAA Division I women's basketball season. The Cowgirls, led by tenth year head coach Jim Littell, played their home games at Gallagher-Iba Arena and were members of the Big 12 Conference.
They finished the season 19–9, 13–5 in Big 12 play to finish in a tie for second place. As the third seed in the Big 12 Tournament the defeated Oklahoma in the Quarterfinals before losing to West Virginia in the Semifinals. They received an at-large bid to the NCAA women's basketball tournament. As the eight seed in the Alamo Regional, the defeated Wake Forest in the First Round before losing to eventual champions Stanford in the Second Round.
The Cowgirls finished the season 15–15, 6–12 in Big 12 play to finish in eighth place. The Big 12 Tournament, NCAA women's basketball tournament and WNIT were all cancelled before they began due to the COVID-19 pandemic.[1]
Source:[2]
|-!colspan=6 style=|Regular season|-!colspan=6 style=| Big 12 Women's Tournament|-!colspan=6 style=| NCAA tournament
2020–21 NCAA Division I women's basketball rankings
| + Regular Season Polls | Poll | Pre- Season | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9 | Week 10 | Week 11 | Week 12 | Week 13 | Week 14 | Week 15 | Week 16 | Final |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AP | RV | RV | RV | RV | RV | RV | RV | |||||||||||
| Coaches | RV | RV | RV | RV | RV | RV | RV | RV |
| Increase in ranking | |||
| Decrease in ranking | |||
| Not ranked previous week | |||
| (RV) | Received Votes | ||
| (NR) | Not Ranked and Did not receive votes |
The Coaches Poll did not release a Week 2 poll and the AP Poll did not release a poll after the NCAA Tournament.