| Nextseason: | 2021–22 |
| Season: | 2020–21 |
| Second League of Serbia | |
| Champions: | Zdravlje |
| Runners Up: | Slodes |
| Teams: | 16 |
| Games: | 22 each |
| Duration: | 3 October 2020 – March 2021 |
| Ppg: | 22.0 |
| Ppg N: | SRB |
| Rpg: | 10.2 |
| Rpg N: | SRB |
| Apg: | 9.0 |
| Apg N: | SRB |
| Winning Streak: | Slodes (8 games) |
| Losing Streak: | Vrbas (22 games) |
The 2020–21 Second Men's League of Serbia is the 15th season of the Second Basketball League of Serbia, the 2nd-tier men's professional basketball league in Serbia.
The season is the first to be played after the previous season was abandoned due to the COVID-19 pandemic in Serbia. The Basketball Federation of Serbia ruled that the 11 teams from the previous season will stay in the league and the highest-placed clubs from four divisions of the First Regional League will be promoted, while the three highest-placed clubs from the previous season will be promoted to the First League.
A total of 16 teams participated in the 2020–21 Second Men's League of Serbia, divided into two geographical groups with 8 clubs.[1]
| Team[5] | City | Arena | Capacity |
|---|---|---|---|
| Beovuk 72 | Belgrade | SC Šumice | 2,000 |
| Bor RTB | Bor | USC Bor | 3,000 |
| Borac Zemun | Belgrade | Pinki Hall | 2,000 |
| Fair Play | Niš | Dušan Radović School Hall | |
| Klik | Arilje | Arilje Sports Hall | |
| Konstantin | Niš | Čair Sports Center | 4,000 |
| Mladost SP | Smederevska Palanka | Vuk Karadžić School Hall | 500 |
| Napredak Junior | Kruševac | Kruševac Sports Hall | 2,500 |
| Proleter Naftagas | Zrenjanin | Crystal Hall | 3,000 |
| Radnički | Belgrade | Radnički SD Hall | |
| Slodes | Belgrade | Slodes Hall | 2,000 |
| Star | Novi Sad | SPC Vojvodina | 1,030 |
| Sveti Đorđe | Žitište | Nikola Tesla School Hall | |
| Vrbas | Vrbas | CFK Drago Jovović | 2,500 |
| Zdravlje | Leskovac | SRC Dubočica | 3,600 |
| Železničar | Čačak | Borac Hall | 4,000 |
| Team | Head coach | Coaching changes |
|---|---|---|
| Beovuk 72 |  Nikola Stanić | |
| Bor RTB | Miloš Nejkov | Dejan Aleksić (until Aug 2020) |
| Borac Zemun | Vedran Popović | |
| Fair Play | Vladan Glavinić | Saša Jović (until Aug 2020) |
| Klik | Miljan Marjanović | |
| Konstantin | Marko Cvetković | Marko Cvetković (until Nov 2020) Dušan Radović (Nov 2020 – N/A) |
| Mladost SP | Zlatan Rakić | Milovan Bogojević (until Aug 2020) |
| Napredak Junior | Ljubiša Damjanović | Vladimir Mišković (until Aug 2020) |
| Proleter Naftagas | Stefan Atanacković | |
| Radnički | Nebojša Knežević | Goran Vučković (until Aug 2020) |
| Slodes | Marko Boras | |
| Sveti Đorđe | Nenad Vignjević | |
| Star | Dimitrije Živković | |
| Vrbas | Petar Bodrožić | Bojan Marković (until Aug 2020) |
| Zdravlje | Lazar Spasić | |
| Železničar | Aleksandar Bjelić | Branko Jorović (until Jul 2020) |