| Mode: | Basketball |
| Sex: | men |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | Presbyterian Blue Hose |
| Conference: | Big South Conference |
| Short Conf: | Big South |
| Record: | 7–15 |
| Conf Record: | 5–12 |
| Hc Year: | 2nd |
| Asst Coach1: | Ben Korren |
| Asst Coach2: | Trey Meyer |
| Asst Coach3: | Nick Lagroone |
The 2020–21 Presbyterian Blue Hose men's basketball team represented Presbyterian College during the 2020–21 NCAA Division I men's basketball season. The team was led by second-year head coach Quinton Ferrell, and played their home games at Templeton Physical Education Center in Clinton, South Carolina as members of the Big South Conference.
The Blue Hose finished the 2019–20 season 10–22, 7–11 in Big South play, to finish in a three-way tie for seventh place. They lost in the first round of the Big South tournament to Charleston Southern.
|-!colspan=12 style=|Regular season|-!colspan=9 style=|Big South tournament|-|-Source:[1]