| Mode: | Basketball |
| Sex: | none |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | Mississippi Valley State Delta Devils |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Record: | 2–22 |
| Conf Record: | 2–13 |
| Hc Year: | 2nd |
| Asst Coach1: | Alan Perry |
| Asst Coach2: | Will Vance |
The 2020–21 Mississippi Valley State Delta Devils basketball team represented Mississippi Valley State University during the 2020–21 NCAA Division I men's basketball season. The team was led by second-year head coach Lindsey Hunter, and played their home games at Harrison HPER Complex in Itta Bena, Mississippi as a member of the Southwestern Athletic Conference. In March, they were the worst ranked team in NCAA Division I according to Kenpom,[1] with the least efficient offense and defense.
|-!colspan=12 style=|Non-conference regular season|-!colspan=12 style=|SWAC regular season|-!colspan=9 style=|SWAC tournament[2]