| Mode: | Basketball |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | La Salle Explorers |
| Conference: | Atlantic 10 Conference |
| Short Conf: | A-10 |
| Record: | 9–16 |
| Conf Record: | 6–11 |
| Hc Year: | 3rd |
| Asst Coach1: | Kyle Griffin |
| Asst Coach2: | Donnie Carr |
The 2020–21 La Salle Explorers basketball team represented La Salle University during the 2020–21 NCAA Division I men's basketball season. The Explorers, led by third-year head coach Ashley Howard, played their home games at Tom Gola Arena in Philadelphia, Pennsylvania as members of the Atlantic 10 Conference. They finished the season 9–16, 6–11 in A-10 Play to finish in 12th place. They lost in the first round of the A-10 tournament to Saint Joseph's.
The Explorers finished the 2019–20 season 15–15, 6–12 in A-10 play to finish in tenth place. Their season ended when the A-10 tournament and all other postseason tournaments were canceled due to the ongoing COVID-19 pandemic.
| Name | Number | Pos. | Height | Weight | Year | Hometown | Reason for departure | |
|---|---|---|---|---|---|---|---|---|
| Ayinde Hakim | 0 | G | 5'11" | 165 | Sophomore | Midseason transfer to UMass Lowell | ||
| Isaiah Deas | 10 | G | 6'6" | 200 | Senior | Graduated | ||
| Ed Croswell | 11 | F | 6'8" | 250 | Sophomore | Transferred to Providence | ||
| Saul Phiri | 13 | G | 6'4" | 215 | Senior | Graduated | ||
| Brandon Stone | 23 | F | 6'11" | 200 | Sophomore | Midseason transfer to Robert Morris | ||
| Moustapha Diagne | 35 | F | 6'9" | 230 | RS Senior | Graduated |
|-!colspan=9 style=| Regular season|-!colspan=9 style=| Atlantic 10 tournamentSource[1]