| Club: | Kayserispor |
| Season: | 2020–21 |
| Chrtitle: | Chairman |
| Chairman: | Berna Gözbaşı |
| Mgrtitle: | Manager |
| Manager: | Bayram Bektaş (until 1 November) Samet Aybaba (from 11 November to 4 January) Dan Petrescu (from 10 January) |
| Stadium: | Kadir Has Stadium |
| League: | Süper Lig |
| League Result: | 17th |
| Cup1: | Turkish Cup |
| Cup1 Result: | Fourth round |
| League Topscorer: | Pedro Henrique (6) |
| Season Topscorer: | Pedro Henrique (6) |
| Pattern B1: | _kayserispor1920h |
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| Pattern B2: | _kayserispor2021a |
| Pattern Ra2: | _nikevapor1920bb |
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| Pattern B3: | _kayserispor2021t |
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| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 Kayserispor season was the club's 55th season in existence and the club's sixth consecutive season in the top flight of Turkish football. In addition to the domestic league, Kayserispor participated in this season's editions of the Turkish Cup. The season covered the period from July 2020 to 30 June 2021.
| scope=col | Player | Transferred from | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15 | TBD |
| scope=col | Player | Transferred to | scope=col; style="width: 65px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 15 | TBD |
See main article: 2020–21 Süper Lig.
See main article: 2020–21 Turkish Cup.