| Mode: | Women's Basketball |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | James Madison Dukes |
| Conference: | Colonial Athletic Association |
| Short Conf: | CAA |
| Record: | 14–10 |
| Conf Record: | 9–6 |
| Head Coach: | Sean O'Regan |
| Hc Year: | 5th |
| Asst Coach1: | Ashley Langford |
| Asst Coach2: | Ian Caskill |
| Asst Coach3: | Samantha Prahalis-Holmes |
| Stadium: | Atlantic Union Bank Center |
The 2020–21 James Madison Dukes women's basketball team represented James Madison University during the 2020–21 NCAA Division I women's basketball season. The Dukes, led by fifth-year head coach Sean O'Regan, played their home games at the Atlantic Union Bank Center as members of the Colonial Athletic Association (CAA). This was the first season the Dukes played their games at the new arena. They finished the season 14–10, 9–6 in CAA play. They received the number two seed in the CAA women's tournament and were eventually eliminated in the semifinal round of the tournament. They were not invited to any additional post-season play.
See main article: 2019–20 James Madison Dukes women's basketball team.
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