| Club: | Guingamp |
| Season: | 2020–21 |
| Chrtitle: | President |
| Chairman: | Bertrand Desplat |
| Mgrtitle: | Head coach |
| Manager: | Sylvain Didot (until 30 August) Mehmed Baždarević (from 30 August to 1 February) Frédéric Bompard (from 1 February) |
| Stadium: | Stade de Roudourou |
| League: | Ligue 2 |
| League Result: | 9th |
| Cup1: | Coupe de France |
| Cup1 Result: | Eighth round |
| League Topscorer: | Yannick Gomis (9) |
| Season Topscorer: | Yannick Gomis (9) |
| Pattern La1: | _guingamp2021h |
| Pattern B1: | _guingamp2021h |
| Pattern Ra1: | _guingamp2021h |
| Pattern Sh1: | _guingamp2021h |
| Pattern So1: | _guingamp2021h |
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| Pattern La2: | _guingamp2021a |
| Pattern B2: | _guingamp2021a |
| Pattern Ra2: | _guingamp2021a |
| Pattern Sh2: | _guingamp2021a |
| Pattern So2: | _guingamp2021a |
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| Pattern La3: | _guingamp2021t |
| Pattern B3: | _guingamp2021t |
| Pattern Ra3: | _guingamp2021t |
| Pattern Sh3: | _guingamp2021h |
| Pattern So3: | _caen1617a |
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| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 En Avant Guingamp season was the club's 108th season in existence and its second consecutive season in the second division of French football. In addition to the domestic league, Guingamp participated in this season's edition of the Coupe de France. The season covered the period from 1 July 2020 to 30 June 2021.
See main article: 2020–21 Ligue 2.
The league fixtures were announced on 9 July 2020.[2]
See main article: 2020–21 Coupe de France.