| Competition: | Cypriot First Division Women |
| Season: | 2020–21 |
| Winners: | Apollon Limassol (11th title) |
| Continentalcup1: | Women's Champions League |
| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 Cypriot First Division Women is the twenty-fourth season if the top-flight women's football league in Cyprus. Apollon Ladies F.C. are the defending champions.
The season began on 13 September 2020.