| Mode: | Basketball |
| Year: | 2020–21 |
| Team: | Canisius Golden Griffins |
| Conference: | Metro Atlantic Athletic Conference |
| Short Conf: | MAAC |
| Record: | 7–6 |
| Conf Record: | 7–5 |
| Hc Year: | 5th |
| Asst Coach1: | Chris Hawkins |
| Asst Coach2: | Thurman Schaetzle |
| Asst Coach3: | Calvin Cage |
The 2020–21 Canisius Golden Griffins men's basketball team represented Canisius College in the 2020–21 NCAA Division I men's basketball season. The Golden Griffins, led by fifth-year head coach Reggie Witherspoon, played their home games at the Koessler Athletic Center in Buffalo, New York as members of the Metro Atlantic Athletic Conference (MAAC). They finished the season 7–6, 7–5 in MAAC play, to finish in a tie for fifth place. As the No. 6 seed in the MAAC tournament, they lost in the first round to No. 11 seed Rider 76–78.
The Golden Griffins finished the 2019–20 season 12–20, 7–13 in MAAC play, to finish in tenth place. They lost in the first round of the MAAC tournament to Iona.[1]
|-!colspan=12 style=| MAAC regular season|-!colspan=12 style=| MAAC tournament|-|-Source:[2]