| Club: | Cagliari |
| Season: | 2020–21 |
| Ownertitle: | Owner |
| Owner: | Tommaso Giulini |
| Chrtitle: | President |
| Chairman: | Tommaso Giulini |
| Mgrtitle: | Head coach |
| Manager: | Eusebio Di Francesco (until 22 February) Leonardo Semplici (from 22 February) |
| Stadium: | Sardegna Arena |
| League: | Serie A |
| League Result: | 16th |
| Cup1: | Coppa Italia |
| Cup1 Result: | Round of 16 |
| League Topscorer: | João Pedro (16) |
| Season Topscorer: | João Pedro (16) |
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| Updated: | 22 May 2021 |
| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 season was the 101st season in the existence of Cagliari Calcio and the club's fifth consecutive season in the top flight of Italian football. In addition to the domestic league, Cagliari participated in this season's edition of the Coppa Italia. The season covered the period from 2 August 2020 to 30 June 2021.
| Player | Moving from | Fee | |||
|---|---|---|---|---|---|
 Simone Aresti | Olbia | Free | |||
| Guglielmo Vicario | Perugia | Loan return | |||
| Diego Godín | Internazionale | Free | |||
| Alessandro Tripaldelli | Sassuolo | €3M | |||
 Mattéo Tramoni | AC Ajaccio | €1.5M | |||
| Marko Rog | Napoli | €13M | |||
| Alessandro Deiola | Spezia | Loan return | |||
 Kwadwo Asamoah | Free | ||||
| Alberto Cerri | SPAL | Loan return | |||
| Zito Luvumbo | Primeiro de Agosto | Undisclosed |
| Player | Moving from | Fee | Notes | |||
|---|---|---|---|---|---|---|
| Gabriele Zappa | Pescara | N/A | On loan until June 2021 | |||
| Arturo Calabresi | Bologna | N/A | On loan until June 2021 | |||
| Daniele Rugani | Juventus | N/A | On loan until June 2021 | |||
 Răzvan Marin | Ajax | N/A | On loan until June 2021 | |||
| Alfred Duncan | Fiorentina | N/A | On loan until June 2021 | |||
 Radja Nainggolan | Internazionale | N/A | On loan until June 2021 | |||
| Riccardo Sottil | Fiorentina | N/A | On loan until June 2021 |
| Player | Moving from | Fee | |||
|---|---|---|---|---|---|
 Robin Olsen | A.S. Roma | Loan return | |||
 Rafael | Spezia | Free | |||
| Fabrizio Cacciatore | Released | Free | |||
| Federico Mattiello | Atalanta | Loan return | |||
| Luca Pellegrini | Juventus | Loan return | |||
| Filippo Romagna | Sassuolo | €4M | |||
| Fabio Pisacane | Lecce | €0.8M | |||
| Luca Cigarini | Crotone | Free | |||
 Artur Ioniță | Benevento | €1M | |||
| Nicolò Barella | Internazionale | €25M | |||
| Marko Pajač | Brescia | €0.5M | |||
| Alberto Paloschi | SPAL | Loan return | |||
| Daniele Ragatzu | Olbia | Free | |||
| Adam Ounas | Napoli | Loan return |
| Player | Moving from | Fee | Notes | |||
|---|---|---|---|---|---|---|
| Paolo Faragò | Bologna | N/A | On loan until June 2021 | |||
| Simone Pinna | Ascoli | N/A | On loan until June 2021 | |||
| Riccardo Ladinetti | Olbia | N/A | On loan until June 2021 | |||
| Filip Bradarić | Al-Ain | N/A | On loan until June 2021 | |||
| Federico Marigosu | Olbia | N/A | On loan until June 2021 | |||
| Christian Oliva | Valencia | N/A | On loan until June 2021 | |||
 Damir Ceter | Pescara | N/A | On loan until June 2021 | |||
| Kiril Despodov | Ludogorets Razgrad | N/A | On loan until June 2021 | |||
| Diego Farias | Spezia | N/A | On loan until June 2021 | |||
| Luca Gagliano | Olbia | N/A | On loan until June 2021 |
See main article: 2020–21 Serie A.
The league fixtures were announced on 2 September 2020.[2]
See main article: 2020–21 Coppa Italia.
|-! colspan=14 style="background:#000080; color:#FF0000; text-align:center| Goalkeepers|-! colspan=14 style="background:#000080; color:#FF0000; text-align:center| Defenders|-! colspan=14 style="background:#000080; color:#FF0000; text-align:center| Midfielders|-! colspan=14 style="background:#000080; color:#FF0000; text-align:center| Forwards|-! colspan=14 style="background:#000080; color:#FF0000; text-align:center| Players transferred out during the season
| width=15 | width=15 | width=15 | width=15 | width=145 | Name | width=100 | Serie A | width=100 | Coppa Italia | width=100 | Total | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9 | FW |  | Giovanni Simeone | 5 | 0 | 5 | ||||||||
| 10 | MF | | Joāo Pedro | 5 | 0 | 5 | |||||||||
| 3 | 2 | DF | Diego Godín | 1 | 0 | 1 | |||||||||
| 18 | MF | Nahitan Nández | 1 | 0 | 1 | ||||||||||
| 22 | DF | Charalampos Lykogiannis | 1 | 0 | 1 | ||||||||||
| 24 | MF | | Paolo Faragò | 0 | 1 | 1 | |||||||||
| 33 | MF | | Riccardo Sottil | 1 | 0 | 1 | |||||||||
| Totals | 14 | 1 | 15 | ||||||||||||